口唇类化妆品中锰的人体健康风险评估

Risk assessment of manganese in lip cosmetics

摘要:
目的了解口唇类化妆品中锰的含量与健康风险。
方法开展口唇类化妆品中锰的风险监测，结合每日用量，运用高端暴露分析模式进行评估。
结果264批口唇化妆品中，有249批检出锰元素。检出率为94.3%，中位数为2.63 mg/kg，每日暴露量为3.88×10^-5 mg/kg体重，安全边际为3 608，安全限量为45 mg/kg。
结论口唇类化妆品中锰含量安全状况良好，正常使用量安全风险较低。不可忽视的是有12.5%的样品锰含量超过设定限量，这表明化妆品中锰的含量并非足够安全。

Abstract:
ObjectiveTo determine the level of manganese and assess potential health risks of lip cosmetics.
MethodsAssessment on manganese of lip cosmetics was performed using high-end exposure analysis mode based on the daily dosage.
ResultsIn a total of 264 lip cosmetics samples， manganese was detected in the 249 sample， with a detection rate of 94.3%. Daily exposure was determined to be 3.88×10^-5 mg/kg. Safety margin was 3 608 and safety limit was 45 mg/kg.
ConclusionLevel of manganese in lip cosmetics remains safe. Health risk is low when appropriately used according to the daily usage. However， it is noted that level of manganese exceeds the limits in approximately 10% of the samples， posing a potential health threat.