王庆丰, 周滔. 常熟市367例麻疹疑似病例IgM抗体检测结果分析[J]. 上海预防医学, 2018, 30(12): 1009-1011. DOI: 10.19428/j.cnki.sjpm.2018.18768
引用本文: 王庆丰, 周滔. 常熟市367例麻疹疑似病例IgM抗体检测结果分析[J]. 上海预防医学, 2018, 30(12): 1009-1011. DOI: 10.19428/j.cnki.sjpm.2018.18768
WANG Qing-feng, ZHOU Tao. Test result analysis on IgM antibody determination in 367 cases of suspected measles in Changshu City[J]. Shanghai Journal of Preventive Medicine, 2018, 30(12): 1009-1011. DOI: 10.19428/j.cnki.sjpm.2018.18768
Citation: WANG Qing-feng, ZHOU Tao. Test result analysis on IgM antibody determination in 367 cases of suspected measles in Changshu City[J]. Shanghai Journal of Preventive Medicine, 2018, 30(12): 1009-1011. DOI: 10.19428/j.cnki.sjpm.2018.18768

常熟市367例麻疹疑似病例IgM抗体检测结果分析

Test result analysis on IgM antibody determination in 367 cases of suspected measles in Changshu City

  • 摘要:
    目的分析常熟市2013—2016年麻疹疑似病例IgM抗体检测结果,为制定和调整麻疹相关防控策略提供依据。
    方法采用酶联免疫吸附试验检测367份麻疹疑似病例血清标本的麻疹IgM抗体。
    结果检出麻疹IgM抗体阳性标本246份,阳性率为67.03%。2015年和2016年发病数增加明显,发病年龄出现向低年龄和大年龄两极移动现象,不同年龄组IgM抗体阳性率差异有统计学意义(χ2=27.03,P<0.01)。麻疹发病主要分布在3—8月,距出疹后不同时间采血IgM抗体阳性检出率差异有统计学意义(χ2=13.62,P<0.01)。
    结论应继续做好麻疹疫苗强化免疫以及查漏补种工作,提高辖区内适龄儿童含麻疹疫苗接种率,加强对流动人口的麻疹监测,提高流动人口、成人以及育龄妇女麻疹疫苗的补种或复种率,提高麻疹高发人群的免疫水平。

     

    Abstract:
    ObjectiveTo analyze the IgM antibody detection results for suspected cases of measles from 2013 to 2016 in Changshu City, in order to provide basis for formulation of strategies of prevention and control of measles.
    MethodsThe serum samples of 367 suspected measles cases were detected for measles IgM by enzyme linked immunosorbent (ELISA) methods.
    ResultsThe serum samples of 246 suspected measles cases were measles IgM positive, the positive rate being 67.03%.The number of cases of measles obviously increased in 2015 and 2016, and the paroxysm of measles tended to occur in the population of low and older ages, showing dipolar pattern.The differences of IgM antibody between different age groups had statistical significance(χ2=27.03, P<0.01).Measles broke out mainly from March to August, when there were obvious differences on the positivity of IgM antibody detected at different times after rash occurrence(χ2=13.62, P<0.01).
    ConclusionMeasles immunization should be enhanced and measles vaccination replenished properly.It is also necessary to raise the rate of measles vaccination among children of suitable age within the jurisdiction.Strengthen monitoring on measles in floating population, enhance vaccine replanting and revaccination of measles in floating population, adult and fertile women and enhance immune level in high incidence population.

     

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