符移才, 吴玉霞. 体外过敏筛选:从研究到管理毒理学[J]. 上海预防医学, 2019, 31(8): 696-702. DOI: 10.19428/j.cnki.sjpm.2019.19231
引用本文: 符移才, 吴玉霞. 体外过敏筛选:从研究到管理毒理学[J]. 上海预防医学, 2019, 31(8): 696-702. DOI: 10.19428/j.cnki.sjpm.2019.19231
FU Yi-cai, WU Yu-xia. In vitro allergy screening:from lab to regulatory toxicology[J]. Shanghai Journal of Preventive Medicine, 2019, 31(8): 696-702. DOI: 10.19428/j.cnki.sjpm.2019.19231
Citation: FU Yi-cai, WU Yu-xia. In vitro allergy screening:from lab to regulatory toxicology[J]. Shanghai Journal of Preventive Medicine, 2019, 31(8): 696-702. DOI: 10.19428/j.cnki.sjpm.2019.19231

体外过敏筛选:从研究到管理毒理学

In vitro allergy screening:from lab to regulatory toxicology

  • 摘要: 管理毒理学与各国的经济和社会状况密切相关,随着毒理学的飞速发展,体外安全性评价的技术竞争变得越来越重要。体外替代方法从基础研究、科学验证、监管认可走过了风云激荡的岁月。与此相关的各学科也随之突飞猛进,本文以体外过敏筛选为例,探讨化学品安全性评价的研究理念的进展。为此,我们建议应当鼓励国家和企业的积极投入,充分利用新技术建立适合我国的、且与国际接轨的毒理学方法是极其重要和非常紧迫的。

     

    Abstract: Regulatory toxicology (RT) is closely associated with economic and social conditions in each country.With rapid development of toxicology, in vitro evaluation technology competition has become more and more important.In vitro alternative methods experienced the agitation of turbulent years through basic research, scientific verification and regulatory approval.Along with the situation, the related disciplines also advanced by leaps and bounds.This paper takes in vitro allergy screening as the example, exploring the progress of the research concept of chemical safety evaluation.It is proposed to encourage active input from the state and enterprises.And it is important and urgent to make full use of the new technology to establish toxicological methods suitable for our country and in line with international standards.

     

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