Abstract: On January 30, 2019, National Health Commission of the People′s Republic of China issued WS/T 647-2019 "Hygienic requirement for lysostaphin and lysozyme disinfectants"(hereinafter referred to as "the Standard"), which was implemented on July 1, 2019.This paper analyses the importance and significance of promulgation of "the Standard" from the aspects of necessity and socio-economic benefits of formulating the hygienic requirements of lysostaphin and lysozyme disinfectants.And interpretation of key indicators is made, especially focusing on the setting of the effective composition content of lysostaphin and lysozyme disinfectants, determination of test methods, as well as stability judgement method. Users of the disinfectants are guaranteed for accurate understanding and better implementing of "the Standard".