赵沛, 蒋栋铭, 鲜林峰, 林剑生, 柳东红, 张丽娟, 余红平, 曹广文. 20042018年中国大陆地区原发性肝癌死亡率分析[J]. 上海预防医学, 2021, 33(10): 881-886. DOI: 10.19428/j.cnki.sjpm.2021.21080
引用本文: 赵沛, 蒋栋铭, 鲜林峰, 林剑生, 柳东红, 张丽娟, 余红平, 曹广文. 20042018年中国大陆地区原发性肝癌死亡率分析[J]. 上海预防医学, 2021, 33(10): 881-886. DOI: 10.19428/j.cnki.sjpm.2021.21080
ZHAO Pei, JIANG Dong-ming, XIAN Lin-feng, LIN Jian-sheng, LIU Dong-hong, ZHANG Li-juan, YU Hong-ping, CAO Guang-wen. Mortality analysis of primary liver cancer in the mainland of China from 2004 to 2018[J]. Shanghai Journal of Preventive Medicine, 2021, 33(10): 881-886. DOI: 10.19428/j.cnki.sjpm.2021.21080
Citation: ZHAO Pei, JIANG Dong-ming, XIAN Lin-feng, LIN Jian-sheng, LIU Dong-hong, ZHANG Li-juan, YU Hong-ping, CAO Guang-wen. Mortality analysis of primary liver cancer in the mainland of China from 2004 to 2018[J]. Shanghai Journal of Preventive Medicine, 2021, 33(10): 881-886. DOI: 10.19428/j.cnki.sjpm.2021.21080

20042018年中国大陆地区原发性肝癌死亡率分析

Mortality analysis of primary liver cancer in the mainland of China from 2004 to 2018

  • 摘要:
    目的 对中国大陆地区2004—2018年原发性肝癌的死亡信息进行分析,评估中国原发性肝癌的死亡情况和变化趋势。
    方法 收集整理2004—2018年中国国家死亡率监测系统的死亡证明数据,应用Joinpoint 回归模型计算不同年龄、不同地区和不同生活环境中原发性肝癌的粗死亡率(CMR)和年龄标准化死亡率(ASMR),分析原发性肝癌死亡基本情况和变化趋势。
    结果 2004—2018年中国原发性肝癌共死亡556 241例,CMR为25.18/10万,ASMR为17.98/10万,原发性肝癌死亡率呈下降趋势。我国城市ASMR为15.56/10万,农村ASMR为19.29/10万。城市男性和女性CMR分别为32.89/10万和12.14/10万;农村男性和女性CMR分别为38.39/10万和14.02/10万。我国东部城市、中部城市和西部城市的CMR分别为22.25/10万、22.66/10万和23.50/10万;东部农村、中部农村和西部农村的CMR分别为27.82/10万、26.98/10万和23.85/10万。我国城市地区0~19岁、20~39岁、40~59岁和≥60岁等4个年龄组中,原发性肝癌的CMR分别为0.14/10万、2.59/10万、24.51/10万、91.80/10万;农村地区上述4个年龄组的CMR分别为0.17/10万、4.05/10万、32.16/10万、103.02/10万。
    结论 中国原发性肝癌死亡率虽呈下降趋势,但由于中国人口基数大,老龄化问题严重,城乡差异及男女性别差异明显,原发性肝癌死亡负担仍然十分严重。

     

    Abstract:
    Objective To determine the mortality and changing trend of primary liver cancer by using the death data of Chinese mainland from 2004 to 2018.
    Methods The death certificate data was collected from China National Mortality Surveillance System from 2004 to 2018. The crude mortality rate(CMR)and age-standardized mortality rate(ASMR)of primary liver cancer in different ages, regions and living environments were calculated by Joinpoint regression model to analyze the basic situation and mortality trend.
    Results From 2004 to 2018, there were 556 241 primary liver cancer deaths in China, with a CMR of 25.18/105 and an ASMR of 17.98/105. It suggested that the mortality of primary liver cancer was on a decreasing trend. During the 15 years, the ASMR of primary liver cancer was 15.56/105 in urban areas and 19.29/105in rural areas. In urban areas, CMR was 32.89/105in males and 12.14/105 in females, respectively; while in rural areas, CMR was 38.39/105 in males and 14.02/105 in females, respectively. The CMR in eastern, central and western urban regions was 22.25/105, 22.66/105 and 23.50/105, respectively. The CMR in the rural areas of these three regions was 27.82/105, 26.98/105 and 23.85/105, respectively. The patients were divided into four age groups: 0-19 years old, 20-39 years old, 40-59 years old, and more than 60 years old. The CMR of four groups in urban areas was 0.14/105, 2.59/105, 24.51/105 and 91.80/105. In rural areas, the CMR of four groups was 0.17/105, 4.05/105, 32.16/105 and 103.02/105.
    Conclusion From 2004 to 2018, the mortality rate of liver cancer in China has a decreasing trend. However, the primary liver cancer death burden is still serious because of the large population base, severe aging population problem, and significant urban-rural and male-female disparities in China.

     

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