曹艳芬, 何淑娴, 项丽芬, 高洁, 杨跃诚, 唐仁海, 叶润华, 王继宝, 何纳, 丁盈盈, 段松. 2019—2020年云南德宏傣族景颇族自治州境内新报告缅甸籍HIV感染者首次CD4+T淋巴细胞计数的临床意义[J]. 上海预防医学, 2022, 34(9): 848-853. DOI: 10.19428/j.cnki.sjpm.2022.21958
引用本文: 曹艳芬, 何淑娴, 项丽芬, 高洁, 杨跃诚, 唐仁海, 叶润华, 王继宝, 何纳, 丁盈盈, 段松. 2019—2020年云南德宏傣族景颇族自治州境内新报告缅甸籍HIV感染者首次CD4+T淋巴细胞计数的临床意义[J]. 上海预防医学, 2022, 34(9): 848-853. DOI: 10.19428/j.cnki.sjpm.2022.21958
shu
CAO Yanfen, HE Shuxian, XIANG Lifen, GAO Jie, YANG Yuecheng, TANG Renhai, YE Runhua, WANG Jibao, HE Na, DING Yingying, DUAN Song. Clinical implications of first CD4+T cell counts among newly reported HIV-infected Burmese in Dehong Prefecture of Yunnan Province in 2019 and 2020[J]. Shanghai Journal of Preventive Medicine, 2022, 34(9): 848-853. DOI: 10.19428/j.cnki.sjpm.2022.21958
Citation: CAO Yanfen, HE Shuxian, XIANG Lifen, GAO Jie, YANG Yuecheng, TANG Renhai, YE Runhua, WANG Jibao, HE Na, DING Yingying, DUAN Song. Clinical implications of first CD4+T cell counts among newly reported HIV-infected Burmese in Dehong Prefecture of Yunnan Province in 2019 and 2020[J]. Shanghai Journal of Preventive Medicine, 2022, 34(9): 848-853. DOI: 10.19428/j.cnki.sjpm.2022.21958
shu

2019—2020年云南德宏傣族景颇族自治州境内新报告缅甸籍HIV感染者首次CD4+T淋巴细胞计数的临床意义

Clinical implications of first CD4+T cell counts among newly reported HIV-infected Burmese in Dehong Prefecture of Yunnan Province in 2019 and 2020

    摘要
  • 摘要:
    目的 了解德宏傣族景颇族自治州（简称“德宏州”）境内2019―2020年新报告缅甸籍人类免疫缺陷病毒（HIV）感染者的一般人口学特征和高危行为，以及首次CD4+T淋巴细胞（简称“CD4细胞”）计数水平。
    方法 对德宏州2019―2020年新报告的境内缅甸籍HIV感染者进行横断面调查，收集相关信息并检测其首次CD4细胞计数。
    结果 共调查1 228例缅甸籍HIV感染者，其中男846例（68.9%），女382例（31.1%）；来自克钦邦445例（36.2%）、掸邦210例（17.1%）。所有调查对象中，有960例（78.2%）参加了首次CD4细胞计数检测，405例（42.2%）首次CD4细胞计数<350 个·μL-1。多因素logistic回归分析显示：年龄≥30岁（OR=1.44，95%CI：1.07~1.92）和在缅甸境内有共针吸毒史（OR=0.41，95%CI：0.21~0.79）是首次CD4细胞计数<350 个·μL-1的影响因素。
    结论 德宏州境内新报告缅甸籍HIV感染者首次CD4细胞计数水平总体较低，尤其是年龄≥30岁和在缅甸境内有注射吸毒史的HIV感染者，应尽早发现境内缅甸籍HIV感染者并及时纳入综合管理。

     

    Abstract:
    Objective To investigate the demographic characteristics， high-risk behavior and first CD4+T cell（CD4 cell） counts among newly reported HIV-infected Burmese in Dehong Dai Jingpo Autonomous Prefecture （Dehong Prefecture） from 2019 to 2020.
    Methods A cross-sectional survey was conducted among newly reported HIV-infected Burmese cases in Dehong Prefecture from 2019 to 2020 to collect related information and measure their first CD4 cell counts.
    Results Among 1 228 HIV-infected Burmese cases， 846 （68.9%） were males and 382 （31.1%） were females； 445 （36.2%） were from Kachin， and 210（17.1%） were from Shan. Of them， 960 cases （78.2%） had participated in the first CD4 cell counts testing， and 405 cases （42.2%） had a first CD4 cell counts <350 cells·μL-1. In the multivariable logistic regression analysis， age ≥30 years （adjusted OR=1.44， 95%CI： 1.07‒1.92） and history of illicit drug use in Myanmar （adjusted OR=0.41， 95%CI： 0.21‒0.79） were independently associated with first CD4 cell counts <350 cells·μL-1.
    Conclusion The first CD4 cell counts are generally low among newly reported HIV-infected Burmese in Dehong Prefecture， especially those aged ≥ 30 years and with a history of intravenous drug use in Myanmar. Therefore， early detection of HIV infection should be strengthened for timely intervention and treatment management among Burmese.

     

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