Objective To ascertain the status and related factors of antiretroviral therapy adherence and analyze the influence of management mode on adherence in HIV infected patients in Jing′an District, Shanghai.

Methods We recruited 150 HIV infected patients who participated in the "peer group care" activities (target group) and those from another 150 patients who did not (control group) but received antiviral treatment during the period from 2015 to 2016 (221 cases in total) into the study.We collected data on general conditions, behavioral way, antiretroviral therapy adherence, life quality, social support, mental status and medical coping modes, and analyzed the related factors of antiretroviral therapy adherence by linear regression model.

Results The 221 HIV infected patients were included, with 124 in target group and 97 in control group.The proportion of good antiretroviral therapy adherence was 86.0%, with 91.9% in target group and 78.4% in control group.Multiple analysis showed that the related factors of antiretroviral therapy adherence were management mode (β=1.871, P < 0.001), disposable income per month (β=0.600, P=0.001), social support utilization (β=0.174, P=0.044) and yield attitude of medical coping modes (β=-0.153, P=0.003).

Conclusion Antiretroviral therapy adherence of HIV infected patients in Jing′an District should be further improved."Peer group level care and management mode" could effectively promote the increase of antiretroviral therapy adherence; however, it should be improved and perfected in the aspects of its coverage and content.