Abstract: Objective To investigate the current status of HIV infection and its epidemiological characteristics among immigrant marriage women in Taizhou prefecture of Zhejiang province. Methods HIV screening was conducted to determine the seroprevalence of HIV infection among women who had migrated to Taizhou city via marriage with local male residents of Taizhou since 1996, during 2006-2012. Further detailed epidemiological description for the HIV infected was conducted based on the Chinese National Information System for AIDS Prevention and Control (CNISAPC). Results A total of 8270 migrant women who had married with local men in Taizhou prefecture of Zhejiang province were included for HIV testing, of whom 26 were found to be infected with HIV, giving a seroprevalence of 0.3144%. By the end of 2012, 54 HIV/AIDS cases including 24 AIDS cases had been diagnosed and registered with CNISAPC. Among them, 24 children were born and 25% (6/24) of the children were infected with HIV. Conclusion Among marriage women from outside Taizhou, a certain percentage of them were infected with HIV. HIV counseling and testing, health education and behavioral interventions are urgently needed for them. It is important to follow up and provide necessary clinical care to HIV-infected individuals to prevent further secondary transmission of HIV between couples and/or from mother to child.