Objective To investigate the awareness rate of AIDS and STDs related knowledge, the epidemic features of high-risk behaviors and related risk factors among pregnant women in a sentinel hospital of Liangxi District of Wuxi City.

Methods The pregnant women who built health care manual or accepted pregnancy health care from April to June in every year during 2010－2015 were investigated.

Results Of more than 2 400 pregnant women investigated, the infection rates of HIV, syphilis, and HCV were 0.04%, 0.46% and 0.25%.The awareness rate of knowledge was 85.79%.But, the understanding of AIDS was not scientific and comprehensive.

Conclusion The infection rates of HIV and other STDs were observed at low levels among pregnant women in the sentinel hospital of Liangxi District.But, some still had high-risk behaviors.The mastery degree of the knowledge of AIDS prevention and control were not comprehensive.Policy advocacy, health education, voluntary consultation test and many other prevention and control strategies must extend the coverage from high risk groups to pregnant women and many other general population.Intensive education about AIDS should be carried out to help people have a correct and scientific understanding of AIDS.