Abstract: Dengue fever is an acute infectious disease caused by dengue virus, which is mainly endemic in tropical and subtropical regions. Dengue virus can be classified into four serological serotypes (DV-1, DV-2, DV-3, and DV-4). All of these serotypes are epidemic in China, but the dominant one thereof is DV-1. Since 1978, dengue fever epidemic has been reported almost every year, especially in the severely-afflicted area, Guangdong province, where more than 40 thousand people were infected with dengue fever in 2014, thus arousing serious public concern. However, even now the public lack the knowledge about dengue fever, thus affecting the effects of prophylactic and control measures for public health. To solve this problem, this paper introduces and analyzes dengue fever in terms of epidemic distribution rules, pathogenic characteristics of virus, clinical features for relevant diseases, prophylactic and control measures for dengue epidemic, etc.