ObjectiveTo understand the maternal positive rate of HBsAg and the neonatal immunization in Huangpu District of Shanghai so as to provide bases for developing strategies of preventing hepatitis B and reducing the rate of neonatal hepatitis B virus infection.

MethodsBy adopting cluster sampling research methods, retrospective surveys were conducted for the detection of HBsAg of the pregnant women from all the obstetric institutions(7 institutions) in Huangpu District of Shanghai as well as for the neonatal hepatitis B vaccinations therein from 2013 to 2015, and statistical analyses were made for the results thereof by utilizing the SPSS 20.0 software.

ResultsA total of 29 425 pregnant women were surveyed and the positive rate of HBsAg thereof was 3.95%. The detection rate of HBsAg(98.42% & 96.76%) as well as the positive rate of HBsAg (2.58% & 4.50%) for both the local and external pregnant women in Shanghai, respectively, showed statistical differences (P < 0.01). The newborns of mothers with positive rates of HBsAg who used combined immunization(HBIG+hepatitis B vaccine) amounted to 1 130, with the rate of combined immunization reaching 98.52%.

ConclusionThe positive rate of HBsAg for the pregnant women in Huangpu District of Shanghai is below the level thereof for those in either the whole country or the other cities and provinces, which shows that Shanghai has made effective achievements in hepatitis B vaccination as well as in the health education relevant thereto. However, active and positive combined immunization measures should still be strengthened for the newborns of mothers with positive rates of HBsAg. In addition, with the growth of pregnant women under new policies, better maternal health care mechanism should be established and various prenatal inspections should be well implemented, thus reducing the rate of the people without taking the detection of HBsAg and preventing newborns from being infected by hepatitis B virus as a result of failing to take timely immunization measures.