何丹丹, 温晓飒, 汤红梅, 陈迪迪, 徐晓莉, 程华. 中小学生血红蛋白水平持续性低下危险因素病例对照研究[J]. 上海预防医学, 2020, 32(8): 675-680. DOI: 10.19428/j.cnki.sjpm.2020.18990
引用本文: 何丹丹, 温晓飒, 汤红梅, 陈迪迪, 徐晓莉, 程华. 中小学生血红蛋白水平持续性低下危险因素病例对照研究[J]. 上海预防医学, 2020, 32(8): 675-680. DOI: 10.19428/j.cnki.sjpm.2020.18990
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HE Dan-dan, WEN Xiao-sa, TANG Hong-mei, CHEN Di-di, XU Xiao-li, CHENG Hua. Case-control study of risk factors for recurrent low hemoglobin level among primary and middle school students[J]. Shanghai Journal of Preventive Medicine, 2020, 32(8): 675-680. DOI: 10.19428/j.cnki.sjpm.2020.18990
Citation: HE Dan-dan, WEN Xiao-sa, TANG Hong-mei, CHEN Di-di, XU Xiao-li, CHENG Hua. Case-control study of risk factors for recurrent low hemoglobin level among primary and middle school students[J]. Shanghai Journal of Preventive Medicine, 2020, 32(8): 675-680. DOI: 10.19428/j.cnki.sjpm.2020.18990
shu

中小学生血红蛋白水平持续性低下危险因素病例对照研究

Case-control study of risk factors for recurrent low hemoglobin level among primary and middle school students

    摘要
  • 摘要:
    目的探索上海市闵行区6~13岁学生血红蛋白水平持续性低下的危险因素，为制定公共卫生政策提供依据。
    方法基于闵行区所有中小学生年度健康体检队列，2013、2014年连续2年对闵行区6~13岁所有参加体检的71 742名学生进行血红蛋白检测。以2次检测血红蛋白均低于标准值的为病例组，正常者为对照组；根据性别、年龄、学校以1 ︰ 1配对，进行问卷调查。以Cox模型拟合1 ︰ 1配对的logistic回归分析危险因素。
    结果母亲孕期贫血(OR=2.32，95%CI：1.49~3.63)、非孕期贫血(OR=4.65，95%CI：1.22~17.69)、孕期与非孕期均贫血(OR=2.51，95%CI：1.50~4.21)、孩子喜好喝浓茶(OR=2.56, 95%CI：1.27~5.13)、偏食(OR=1.94, 95%CI：1.45~2.59)是血红蛋白持续低下的独立危险因素。经常咬玩具(OR=1.79，95%CI：1.10~2.86)、经常咬铅笔(OR=1.80，95%CI：1.25~2.59)、消瘦(OR=3.37，95%CI：1.11~10.21)是血红蛋白持续低下的可能危险因素。
    结论6~13岁学生血红蛋白持续性低下的危险因素与母亲的贫血状态有关，也与自身饮食偏好有关。应加强孕龄期女性健康宣教，培养子女合理饮食习惯，同时尽早治疗。消瘦的学生应是血红蛋白持续性低下的重点关注人群。

     

    Abstract:
    ObjectiveTo explore the risk factors of recurrent low hemoglobin(RLH) level among students from 6 to 13 years old, and to formulate strategies and policies in this regard.
    MethodsSurveillance on hemoglobin concentration was conducted among 71 742 students aged from 6 to 13y between 2013-2014 based on the annual physical examination for primary and middle school in Minhang District.Of those students, 670 were diagnosed with low hemoglobin level according to WHO criteria.A 1 ︰ 1 matched case-control study was conducted based on gender, age and school type.Questionnaire surveys for data collection were analyzed using Cox′s proportional hazards regression.
    ResultsFactors as pregnancy anemia(OR=2.32, 95%CI:1.49-3.63), non-pregnancy anemia(OR=4.65, 95%CI:1.22-17.69), maternal anemia(OR=2.51, 95%CI:1.50-4.21), drinking strong tea(OR=2.56, 95%CI:1.27-5.13) and dietary bias(OR=1.94, 95%CI:1.45-2.59) were risk factors of recurrent low hemoglobin level.Chewing pencils(OR=1.80, 95%CI:1.25-2.59) or toys(OR=1.79, 95%CI:1.10-2.86) and wasting(OR=3.37, 95%CI:1.11-10.21)might be the risk factors.
    ConclusionThe risk factors of recurrent low hemoglobin level among students aged from 6 to 13 years are related to maternal anemia status and their dietary habits.We should strengthen education for women of child-bearing age, and help to develop healthy eating practices for their babies.Emaciated students should be focused on in this regard.

     

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