刘赛朵, 蒋贤高, 宁洪叶, 叶新春, 潘宁, 吴正兴, 周月影, 邱超超, 施伎蝉. 42例新型冠状病毒肺炎的临床特征分析[J]. 上海预防医学, 2020, 32(9): 736-739. DOI: 10.19428/j.cnki.sjpm.2020.20092
引用本文: 刘赛朵, 蒋贤高, 宁洪叶, 叶新春, 潘宁, 吴正兴, 周月影, 邱超超, 施伎蝉. 42例新型冠状病毒肺炎的临床特征分析[J]. 上海预防医学, 2020, 32(9): 736-739. DOI: 10.19428/j.cnki.sjpm.2020.20092
LIU Sai-duo, JIANG Xian-gao, NING Hong-ye, YE Xin-chun, PAN Ning, WU Zheng-xing, ZHOU Yue-ying, QIU Chao-chao, SHI Ji-chan. Clinical features of 42 cases of COVID-19[J]. Shanghai Journal of Preventive Medicine, 2020, 32(9): 736-739. DOI: 10.19428/j.cnki.sjpm.2020.20092
Citation: LIU Sai-duo, JIANG Xian-gao, NING Hong-ye, YE Xin-chun, PAN Ning, WU Zheng-xing, ZHOU Yue-ying, QIU Chao-chao, SHI Ji-chan. Clinical features of 42 cases of COVID-19[J]. Shanghai Journal of Preventive Medicine, 2020, 32(9): 736-739. DOI: 10.19428/j.cnki.sjpm.2020.20092

42例新型冠状病毒肺炎的临床特征分析

Clinical features of 42 cases of COVID-19

  • 摘要:
    目的了解新型冠状病毒肺炎患者的临床特点、实验室检查结果、胸部CT影像表现和治疗方案,分析其与预后的关系。
    方法采用SAS统计学软件回顾性分析2020年1—2月温州市第六人民医院收治并成功治愈的42例新型冠状病毒肺炎患者的临床资料。
    结果42例患者的临床症状常见的有发热(35例)、咳嗽(26例)、乏力(14例)、呼吸费力(9例)、咽痛(4例)、肌肉酸痛(5例)、头痛(2例)、恶心(4例)、腹泻(6例)、腹痛(1例)。血淋巴细胞绝对数有不同程度下降(22例),14例患者乳酸脱氢酶(LDH)升高明显,降钙素原(PCT)无明显变化。影像多表现为两肺外带散在云紊状及磨玻璃状高密度影,局部可见小片状实变,并可见支气管充气征,少数影像表现为弥漫性的高密度,病灶大部实变或条索状改变,局部纤维化形成,以两肺下叶为著。
    结论新型冠状病毒肺炎绝大多数以发热和咳嗽为首发症状,少部分合并有气促及腹泻,伴有不同程度全身症状,但经积极抗病毒、抗感染、改善全身症状及支持治疗后,大部分患者病情改善。该病传染性强,病情变化快,因此,早发现、早诊断及尽早开始全身的综合救治是治疗的关键。

     

    Abstract:
    ObjectiveTo investigate the clinical features, laboratory findings, chest CT findings and treatment of patients with COVID-19, and to analyze their relationship with prognosis.
    MethodsFrom January to February 2020, the clinical data on the 42 patients with COVID-19 admitted to the Wenzhou Sixth People′s Hospital were analyzed retrospectively.
    ResultsThe clinical symptoms of the 42 cases included fever (35 cases), cough (26 cases), fatigue (14 cases), aspiration (9 cases), sore throat (4 cases), muscle ache (5 cases), headache (2 cases), nausea (4 cases), diarrhea (6 cases) and abdominal pain (1 case).The absolute number of blood lymphocyte decreased to different degrees in 22 cases.Fourteen cases had lactate dehydrogenase obviously, with no obvious change in procalcitonin.The imaging manifestations were cloud-like and ground-glass-like high density shadows scattered outside the lungs, small flaky consolidation and bronchus inflating sign were seen locally.A few images showed diffuse high density, most of the lesions showed consolidation or striate change, and local fibrosis was formed in the lower lobes of both lungs.
    ConclusionFever and cough are the first symptoms of COVID-19, and a few cases are associated with shortness of breath and diarrhea, accompanied by different degrees of systemic symptoms, but most of the patients improve their conditions after active antivirus, anti-infection, systematic symptoms improvement and supportive treatment.The disease is highly infectious and its condition changes rapidly.Therefore, early detection, early diagnosis and comprehensive treatment of the whole body as soon as possible are the keys to treatment.

     

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