沈军, 王颖, 西雁, 王春灵, 乔燕, 花佩, 陈慧, 孙琪. 老年高级知识分子患者慢性病与认知功能关系的研究[J]. 上海预防医学, 2020, 32(8): 688-692. DOI: 10.19428/j.cnki.sjpm.2020.20306
引用本文: 沈军, 王颖, 西雁, 王春灵, 乔燕, 花佩, 陈慧, 孙琪. 老年高级知识分子患者慢性病与认知功能关系的研究[J]. 上海预防医学, 2020, 32(8): 688-692. DOI: 10.19428/j.cnki.sjpm.2020.20306
shu
SHEN Jun, WANG Ying, XI Yan, WANG Chun-ling, QIAO Yan, HUA Pei, CHEN Hui, SUN Qi. Relationship between chronic diseases and cognitive function in elderly patients of high intellectuals[J]. Shanghai Journal of Preventive Medicine, 2020, 32(8): 688-692. DOI: 10.19428/j.cnki.sjpm.2020.20306
Citation: SHEN Jun, WANG Ying, XI Yan, WANG Chun-ling, QIAO Yan, HUA Pei, CHEN Hui, SUN Qi. Relationship between chronic diseases and cognitive function in elderly patients of high intellectuals[J]. Shanghai Journal of Preventive Medicine, 2020, 32(8): 688-692. DOI: 10.19428/j.cnki.sjpm.2020.20306
shu

老年高级知识分子患者慢性病与认知功能关系的研究

Relationship between chronic diseases and cognitive function in elderly patients of high intellectuals

    摘要
  • 摘要:
    目的探讨老年高级知识分子患者慢性病与认知功能的相关关系，为预防和延缓老年患者认知功能的衰退提供科学依据。
    方法对入住复旦大学中山医院的65岁以上离退休老年高知患者100例进行一般情况的问卷调查，采用MoCA量表评估认知功能，并收集和记录高血压、冠心病、糖尿病等慢性疾的罹患情况，比较不同认知功能组患者慢性疾病患病率的差异。
    结果100例高知患者中认知功能正常组34例，轻度认知功能障碍组50例，中度认知功能障碍组16例。中度认知功能障碍组中高血压病(93.8%)、冠心病(75.0%)、脑卒中(56.3%)、糖尿病(56.3%)等疾病患病率较高；认知功能正常组相应疾病患病率较低，分别为61.8%，41.2%，17.6%，20.6%，差异有统计学意义(P < 0.05)。而不同认知功能组别间慢性呼吸疾病和肿瘤性疾病的患病率无统计学差异(P>0.05)。患心脑血管及代谢疾病是轻度和中度认知功能障碍的重要危险因素(P=0.002)。
    结论加强心脑血管及代谢疾病的防治，有益于延缓认知功能障碍的发生发展。

     

    Abstract:
    ObjectiveTo determine the relationship between chronic diseases and cognitive function in elderly patients, for the purpose of preventing and alleviating cognitive malfunction.
    MethodsA total of 100 retired high intellectuals with age older than 65 years were enrolled.They were hospitalized in Zhongshan Hospital and were requested to complete a conventional questionnaire.Cognitive function was evaluated by Montreal Cognitive Assessment (MoCA) Scale.Their chronic diseases including hypertension, coronary artery disease, diabetes mellitus were recorded and compared among subjects with different cognitive function levels.
    ResultsBased on MoCA Scale, 34 cases were sorted as having normal cognitive function, 50 cases as mild cognitive impairment, and 16 cases as moderate cognitive impairment.Patients with moderate cognitive impairment showed a significantly higher percentage of hypertension (93.8%), coronary artery disease (75.0%), stroke (56.3%), diabetes mellitus (56.3%) while the patients with normal cognitive function exhibited relatively lower percentage of the above-mentioned diseases (61.8%, 41.2%, 17.6%, 20.6%, respectively, P < 0.05).However such difference was not observed for respiratory disease and neoplastic disease among patients with different cognitive conditions (P>0.05).In addition, cardiovascular and metabolic diseases were found to be important risk factors of mild-to-moderate cognitive impairment (P=0.002).
    ConclusionPrevention and treatment of cardiovascular and metabolic diseases could be imperative to alleviate the process of cognitive impairment.

     

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