钱栋, 强德仁, 施鸿飞, 姚杏娟, 徐文超, 吉俊敏. 江苏省常州市居民血脂比与糖尿病及糖尿病前期的关系[J]. 上海预防医学, 2023, 35(11): 1088-1092. DOI: 10.19428/j.cnki.sjpm.2023.23173
引用本文: 钱栋, 强德仁, 施鸿飞, 姚杏娟, 徐文超, 吉俊敏. 江苏省常州市居民血脂比与糖尿病及糖尿病前期的关系[J]. 上海预防医学, 2023, 35(11): 1088-1092. DOI: 10.19428/j.cnki.sjpm.2023.23173
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QIAN Dong, QIANG Deren, SHI Hongfei, YAO Xingjuan, XU Wenchao, JI Junmin. Relationship of diabetes and prediabetes with lipid ratios in Changzhou Residents of Jiangsu Province[J]. Shanghai Journal of Preventive Medicine, 2023, 35(11): 1088-1092. DOI: 10.19428/j.cnki.sjpm.2023.23173
Citation: QIAN Dong, QIANG Deren, SHI Hongfei, YAO Xingjuan, XU Wenchao, JI Junmin. Relationship of diabetes and prediabetes with lipid ratios in Changzhou Residents of Jiangsu Province[J]. Shanghai Journal of Preventive Medicine, 2023, 35(11): 1088-1092. DOI: 10.19428/j.cnki.sjpm.2023.23173
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江苏省常州市居民血脂比与糖尿病及糖尿病前期的关系

Relationship of diabetes and prediabetes with lipid ratios in Changzhou Residents of Jiangsu Province

    摘要
  • 摘要:
    目的 探讨江苏省常州市35~75岁居民血脂比与糖尿病及糖尿病前期的关联性。
    方法 采用多阶段整群随机抽样方法，调查常州市天宁区和武进区35~75岁常住居民，通过问卷调查、体格检查和实验室检测获得相关数据。采用二分类logistic回归方法分析血脂比与糖尿病及糖尿病前期的关系。
    结果 调查人群中糖尿病患病率为18.69%，糖尿病前期患病率为10.53%；总人群中TC/HDL⁃C、TG/HDL⁃C 和LDL⁃C/HDL⁃C比值最高组人群患糖尿病前期风险均显著增加，分别增加68%、93%和38%；TC/HDL⁃C、TG/HDL⁃C和LDL⁃C/HDL⁃C最高组患糖尿病风险也显著增加，分别增加105%、149%和78%。与男性相比，女性3项血脂比上升均导致糖尿病和糖尿病前期的患病风险增加，关联性较强。
    结论 35~75岁人群中血脂比TC/HDL⁃C、TG/HDL⁃C以及LDL⁃C/HDL⁃C与糖尿病及糖尿病前期风险存在关联性，其中TG/HDL⁃C与糖尿病及糖尿病前期的关联性最强，有望成为评估糖尿病发生发展的重点预测指标。

     

    Abstract:
    Objective To investigate the association of lipid ratios with diabetes and pre-diabetes in residents aged 35-75 years in Changzhou City.
    Methods A multistage whole-group random sampling method was used to survey permanent residents aged 35-75 years in Tianning and Wujin districts of Changzhou City， and the study data were obtained by questionnaires， physical examination and laboratory tests. The relationship between lipid ratios and diabetes and pre-diabetes was analyzed by dichotomous logistic regression method.
    Results The prevalence of diabetes in the surveyed population in Changzhou was 18.69%， and the prevalence of pre-diabetes was 10.53%. In the total population， the risk of pre-diabetes was significantly increased in the highest TC/HDL-C， TG/HDL-C and LDL-C/HDL-C groups， by 68%， 93% and 38%， respectively； the risk of diabetes was also significantly increased in the highest TC/HDL-C， TG/HDL-C and LDL-C/HDL-C groups， by 105%， 149% and 78%， respectively. The risk of diabetes was also significantly increased in the highest TC/HDL-C， TG/HDL-C and LDL-C/HDL-C groups， by 105%， 149% and 78%， respectively. All three lipid ratios increased in women compared to men， leading to a stronger association with increased risk of diabetes and pre-diabetes.
    Conclusion Lipid ratios TC/HDL-C， TG/HDL-C， and LDL-C/HDL-C were correlated with the risk of diabetes and pre-diabetes in people aged 35-75 years， with TG/HDL-C having the strongest association with diabetes and pre-diabetes， and is expected to be a key predictor for assessing the development of diabetes.

     

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