Abstract: Objective To evaluate clinical effect of health education for diabetics in outpatient clinic. Methods A total of 120 patients with type 2 diabetes in our outpatient clinic were divided into 2 groups randomly:experiment and control. The experiment group had 60 patients that received health education, while the control group had 60 patients that did not. Both groups kept the same pharmacotherapy as prior to the education. Fasting plasma glucose (FPG), postprandial 2h glucose (2hPG), glycosylated hemoglobin (HbAlc), triglyceride (TG), total cholesterol (TC), low density lipid cholesterol (LDL-C), and high density lipid cholesterol (HDL-C) were measured before and after health education. Results In the experiment group, levels of FPG, 2hPG, HbA1c were (8.0±1.4) mmol/L, (12.2±2.9) mmol/L, (7.5±1.5)% and (6.5±1.1) mmol/L, (8.3±2.2) mmol/L, (6.1±0.7)% before and after health education respectively,which were different significantly(P<0.05). TG,TC,HDL-C were (2.05±0.99) mmol/L, (5.44±1.04) mmol/L, (1.42±0.36) mmol/L and (1.39±0.63) mmol/L, (4.04±0.78) mmol/L, (1.94±1.01) mmol/L,which were also different significantly(P<0.05). Conclusion Health education in outpatient clinic can improve patients' plasma glucose level and blood lipid level.