ObjectiveTo investigate the clinical significance and treatment of atypical squamous cell lesions (ASCUS) in cervical lesions by analyzing liquid based cytology test in ASCUS.
MethodsAll 1 116 patients with ASCUS were done with HPV typing test and colposcopy, suspicious sites were done with colposcopy biopsy or cervical tube scraping.Pathological examination results were statistically analyzed.
ResultsOf the 1 116 patients with ASCUS, 540 were in high-risk of HPV, 2 were in low-risk HPV.HPV infection rate was 48.57%(542/1 116) and colposcopic biopsy or neck tube scratch curettage and pathological found 827 cases of chronic cervicitis, 116 cases of flat condyloma, 2 cases of condyloma acuminatum (CA), 84 cases of LSIL (cervical intraepithelial low-grade lesions), 79 cases of HSIL (cervical intraepithelial high-grade lesion), and 8 cases of cervical squamous cell carcinoma.In ASCUS women, the incidence of cervical lesions was 25.90% (289/1 116), where the incidence of HSIL was 7.08%, and the incidence of cervical squamous cell carcinoma 0.72%.
ConclusionClinically HPV genotyping can detect the high-risk population with ASCUS, thus reducing unnecessary colposcopy and biopsy, and decreasing the psychological burden of the patients and the waste of medical resources.
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