TORCH infection state and related factors in 23 405 pregnant women in Pudong Area from 2011 to 2016

ObjectiveTo investigate the TORCH(Toxoplasma gondii, Rubella virus, Cytomegalo-virus, and Herpes simplex virus) infections status and related factors among pregnant women in Pudong Area, during 2011-2016.

MethodsChemiluminescence method was used to detect TORCH infections in 23 405 pregnant women who visited Health Hospital for Women and Children of Shanghai Pudong Area from 2011 to 2016.The correlations between TORCH infections and the household registration, pet contact history and pregnant age were analyzed accordingly.

ResultsIn 23 405 samples, the positivity of Cytomegalo virus Immunoglobulin G (IgG), Rubella virus IgG, Rubella virus (Immunoglobulin M) IgM, Toxoplasma gondii IgG, Cytomegalo virus IgM, Toxoplasma gondii IgM was 87.54%, 66.77%, 1.32%, 0.99%, 0.47% and 0.36%, respectively.Upward trend in Toxoplasma gondii positivity was observed during the study period (P < 0.05).The average annual positivity of TOX-IgG and TOX-IgM increased 11.36% and 19.67%, respectively.No statistical difference was found in the positivity of Rubella virus and Cytomegalo virus in the past years.There was statistical correlation between TORCH infections and the pet contact history (P < 0.05).The age of pregnancy, household registry and pet contact history during pregnancy were significantly associated with infections of Toxoplasma gondii and Rubella virus (P < 0.05 for all).

ConclusionTORCH infection rate was increasing in pregnant women in the past years, which were mainly due to the increased Toxoplasma gondii positivity.Feeding pets, rural household registration are the risk factors for TORCH infection.Strengthening the examination of TORCH infections among pregnant women and applying effective medical intervention are of great importance for ensuring the health of pregnant women and fetuses.