Effect analysis of behavioral intervention in elderly patients with asymptomatic hyperuricemia

ObjectiveTo intervene in living behavior and food habits of patients with asymptomatic hyperuricemia over 65 year-old in a community of Shanghai and study the effect.

MethodsA total of 227 patients over 65 year-old from Dapuqiao community in Shanghai in 2013 were selected and randomly assigned into two groups:the intervention group and control group.Behavioral intervention was performed in the intervention group by general practitioner teams, including the establishment of electronic health records, health assessments, guidance on healthy lifestyles, while no above intervention was given in the control group in two years.The serum uric acid and other related test results were compared between the two groups.

ResultsBefore the intervention, there were no significant differences in age, BMI, waist circumference, blood pressure and biochemical indexes between the two groups.The levels of serum uric acid among males:(444.00±18.03)and(442.48±14.60)μmol/L, t=0.432, P=0.667.The levels of serum uric acid among females:(385.36±16.05)and(389.39±17.48)μmol/L, t=-1.309, P=0.193.After 1 year and 2 years′ behavioral intervention, the serum uric acid of the intervention group were significantly lower than that of the control group.The levels of serum uric acid at 1 year after behavioral intervention:the male group were (419.45±24.83) and(437.01±24.44)μmol/L, t=-3.420, P=0.001 while the female group were (354.68±30.26) and (374.35±29.53)μmol/L, tS=-3.588, P=0.000.The levels of serum uric acid at 2 years after behavioral intervention:the male group were (408.73± 34.30) and (435.49±41.31)μmol/L, t=-3.381, P=0.001 while the female group were (317.47±35.81) and (364.58±43.63)μmol/L, t=-6.420, P=0.000. Meanwhile, the levels of fasting blood-glucose and triglyceride in the intervention group were significantly lower than those in the control group(All P < 0.05).

ConclusionThe behavioral intervention can decrease serum uric acid in patients with asymptomatic hyperuricemia, which suggests that the intervention strategy is effective in this regard.