Effect evaluation on intervention for patients with high Hcy and hyperpiesia in the community

ObjectiveTo analyze the effectiveness of intervention over patients with HHcy and explore preventive practices, so as to prevent and reduce the incidence of stroke in the community.

MethodsThe study was a random control design.A total of 1 070 participants with HHcy were recruited from the Huangpu District chronic disease management database.Participants were randomly assigned into intervention group (569 persons), which had personal follow-up and health education intervention.Meanwhile, the control group (501persons) received only personal follow-up.Then the levels of Hcy, lifestyle and body index before and after the intervention were compared between the two groups.

ResultsThe average Hcy value was significantly lower in intervention group compared to that in control group(P < 0.05);but other indexes like BMI, SBP, DBP showed no significant difference between the groups(P>0.05).There were no changes over smoking and drinking rates in both groups(P>0.05).While the intake of vegetable increased in the intervention group(P < 0.05).

ConclusionThe community-based intervention has positive impact on lowering Hcy value among patients with HHcy.Especially improvement of diet structure is an effective way to prevent HHcy.