ZHUO Jiatong.Advantages of COVID-19 vaccine in the T cell immune response[J].Shanghai Journal of Preventive Medicine,2024,36(04):409-414.. doi: 10.19428/j.cnki.sjpm.2024.23382
Citation: ZHUO Jiatong.Advantages of COVID-19 vaccine in the T cell immune response[J].Shanghai Journal of Preventive Medicine,2024,36(04):409-414.. doi: 10.19428/j.cnki.sjpm.2024.23382

Advantages of COVID-19 vaccine in the T cell immune response

  • Objective To illustrate the mechanism of COVID-19 vaccine in the T cell immune response.
    Methods Based on the characteristics of T cell and B cell immune response, we matched the data of incubation periods across the SARS-CoV-2 prototype strain, Delta variants, and Omicron variants and effectiveness of mRNA and inactivated COVID-19 vaccines for analysis.
    Results The effectiveness of mRNA COVID-19 vaccine against infection and onset was consistent with incubation period principally being ≥5 days. In contrast, the effectiveness of inactivated COVID-19 vaccine was consistent with incubation period principally being ≥8 days.
    Conclusion It may be interpreted by faster T cell immune response stimulated by mRNA vaccine, compared to B cell immune response by inactivated vaccine.
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