Test results analysis on wild measles virus neutralizing antibodies in 70 pairs of mother and infant

Objective To investigate the level of wild-measles neutralization antibody of both mother and infant, and its correlation between the paired mother and infant. Methods The wild-measles neutralization antibody in the serum of the women and their infants were detected directly by a neutralization test (NT) methods. Results The positivity rates of neutralization antibody in mothers and their infants were 91.52% and 88.57% respectively, geometric mean title of neutralization antiboby(GMT) being 61.32 and 58.17 respectively. And the titer of neutralization antibody was highly correlated (r=0.899, P<0.01) between mother and infant in pairs. When the GMT of mother was ≥ 1:16,the positivity rate of neutralization antibody in their infants might reach 100.00%. Conclusion It is important to increase the maternal measles antibody level in order to prevent infants from measles.