Abstract: Grassroots innovation is a powerful tool for deepening reform in an all-round way.With the further deepening of the reform of the medical system, the traditional image of the Center for Disease Control and Prevention (CDC) is gradually changing to be scientific and technological innovation.Youth is the engines of innovation, and CDC is the pioneer to promote medical community, as the teaching base for public health relevant disciplines in colleges.Therefore, how CDC could play a leading role in the training of public health youth talents is worth discussing deeply.