顾文超, 李勇, 吴婷婷, 黄晶晶, 陈俊, 闫浩, 黄文静, 张玉, 赖淼菊, 唐海丰. 上海市普陀区20132019年诺如病毒感染性腹泻流行特征分析[J]. 上海预防医学, 2021, 33(12): 1141-1145. DOI: 10.19428/j.cnki.sjpm.2021.20629
引用本文: 顾文超, 李勇, 吴婷婷, 黄晶晶, 陈俊, 闫浩, 黄文静, 张玉, 赖淼菊, 唐海丰. 上海市普陀区20132019年诺如病毒感染性腹泻流行特征分析[J]. 上海预防医学, 2021, 33(12): 1141-1145. DOI: 10.19428/j.cnki.sjpm.2021.20629
GU Wen-chao, LI Yong, WU Ting-ting, HUANG Jing-jing, CHEN Jun, YAN Hao, HUANG Wen-jing, ZHANG Yu, LAI Miao-ju, TANG Hai-feng. Analysis of norovirus surveillance in adult infectious diarrhea in Putuo District of Shanghai[J]. Shanghai Journal of Preventive Medicine, 2021, 33(12): 1141-1145. DOI: 10.19428/j.cnki.sjpm.2021.20629
Citation: GU Wen-chao, LI Yong, WU Ting-ting, HUANG Jing-jing, CHEN Jun, YAN Hao, HUANG Wen-jing, ZHANG Yu, LAI Miao-ju, TANG Hai-feng. Analysis of norovirus surveillance in adult infectious diarrhea in Putuo District of Shanghai[J]. Shanghai Journal of Preventive Medicine, 2021, 33(12): 1141-1145. DOI: 10.19428/j.cnki.sjpm.2021.20629

上海市普陀区20132019年诺如病毒感染性腹泻流行特征分析

Analysis of norovirus surveillance in adult infectious diarrhea in Putuo District of Shanghai

  • 摘要:
    目的了解上海市普陀区成人感染性腹泻病例中诺如病毒的感染情况和流行特征,为诺如病毒引起的感染性腹泻病的防控提供依据。
    方法收集2013年1月—2019年12月普陀区成人感染性腹泻病综合监测点医院腹泻病例的粪便标本、临床特征和流行病学资料,采用实时荧光定量反转录-聚合酶链式反应(rRT-PCR)检测诺如病毒,并分析病例诺如病毒的监测结果。
    结果1 389例成人感染性腹泻病例中,诺如病毒阳性检出率为25.41%,男性检出率(27.16%)高于女性(23.89%);353例诺如病毒阳性病例中,诺如病毒GⅡ组感染最多(占77.98%);年龄为30~44岁病例的诺如病毒阳性率最高,春季、秋季和冬季是诺如病毒感染的高发季节(9月—次年5月)。诺如病毒阳性病例恶心、呕吐、肠鸣音亢进、水样便等症状的构成比均高于诺如病毒阴性病例,差异有统计学意义(P<0.05)。
    结论上海市普陀区成人感染性腹泻病例的诺如病毒检出率高,主要组别为诺如病毒GⅡ组,除夏季外均是诺如病毒高发季节,应在高发季节针对重点人员加强诺如病毒的监测和健康宣传等防控措施。

     

    Abstract:
    ObjectiveTo investigate the prevalence and epidemiological characteristics of norovirus in adult cases with infectious diarrhea in Putuo District of Shanghai, and provide scientific evidence for the prevention and control of infectious diarrhea caused by norovirus.
    MethodsFecal samples, clinical information and epidemiological data were collected from January 2013 through December 2019 in surveillance hospitals in Putuo District of Shanghai. Norovirus was examined by real-time fluorescent quantitative reverse transcription polymerase chain reaction (rRT-PCR).
    ResultsIn 1 389 adult cases with infectious diarrhea, norovirus positive rate was 25.41%, which was significantly higher in male (27.16%) than female (23.89%). Furthermore, in 353 cases positive for norovirus, GⅡ group was the most common (77.98%).The positive rate was highest in the cases aged 30-44 years. Spring, autumn and winter were the seasons with higher incidence of norovirus (September to May). The norovirus-infected cases had more nausea, vomiting, hyperactivity of bowel sounds, and watery stool, compared to the negative cases (P<0.05).
    ConclusionThe detection rate of norovirus remains high in adult cases with infectious diarrhea in Putuo District of Shanghai, of which GII is predominant. Seasonality may be spring, autumn and winter. Therefore, it warrants the countermeasures, such as surveillance and health education, for prevention and control of norovirus in susceptible population during epidemic seasons.

     

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