肖文佳, 匡小舟, 张静, 杨吉星, 南园, 姚虹, 滕峥, 林声, 宫霄欢, 俞晓, 潘浩, 张曦. 上海市某老年福利院一起诺如病毒性腹泻暴发疫情的调查[J]. 上海预防医学, 2022, 34(8): 765-769. DOI: 10.19428/j.cnki.sjpm.2022.21625
引用本文: 肖文佳, 匡小舟, 张静, 杨吉星, 南园, 姚虹, 滕峥, 林声, 宫霄欢, 俞晓, 潘浩, 张曦. 上海市某老年福利院一起诺如病毒性腹泻暴发疫情的调查[J]. 上海预防医学, 2022, 34(8): 765-769. DOI: 10.19428/j.cnki.sjpm.2022.21625
XIAO Wenjia, KUANG Xiaozhou, ZHANG Jing, YANG Jixing, NAN Yuan, YAO Hong, TENG Zheng, LIN Sheng, GONG Xiaohuan, YU Xiao, PAN Hao, ZHANG Xi. An outbreak of norovirus diarrhea in a welfare home for the elderly in Shanghai[J]. Shanghai Journal of Preventive Medicine, 2022, 34(8): 765-769. DOI: 10.19428/j.cnki.sjpm.2022.21625
Citation: XIAO Wenjia, KUANG Xiaozhou, ZHANG Jing, YANG Jixing, NAN Yuan, YAO Hong, TENG Zheng, LIN Sheng, GONG Xiaohuan, YU Xiao, PAN Hao, ZHANG Xi. An outbreak of norovirus diarrhea in a welfare home for the elderly in Shanghai[J]. Shanghai Journal of Preventive Medicine, 2022, 34(8): 765-769. DOI: 10.19428/j.cnki.sjpm.2022.21625

上海市某老年福利院一起诺如病毒性腹泻暴发疫情的调查

An outbreak of norovirus diarrhea in a welfare home for the elderly in Shanghai

  • 摘要:
    目的 调查上海市某老年福利院一起诺如病毒性腹泻暴发疫情,分析疫情的流行病学和病毒基因型特征。
    方法 明确病例定义并采用统一的调查表对病例开展个案调查,结合现场流行病学调查和实验室检测结果综合分析。
    结果 疫情历时14 d,共报告病例23例,罹患率12.37%(23/186),其中男性3例,女性20例。该老年福利院主楼1、4和6层病例较多,占52.17%(12/23)。主楼共报告病例19例,罹患率11.59%(19/164);副楼共报告病例4例,罹患率18.18%(4/22),主楼与副楼的罹患率差异无统计学意义(χ2=0.779,P>0.05)。临床表现主要以呕吐、腹泻为主。该老年福利院老人、护理人员、其他工作人员呕吐症状发生率差异有统计学意义(χ2=10.216,P<0.05),但腹泻症状发生率差异无统计学意义(χ2=1.218,P>0.05)。共采集23份病例、1份病例家属、68份风险人员粪便标本和14份环境表面涂抹标本,在19份病例、1份病例家属和36份风险人员粪便标本中检测出诺如病毒GⅡ型阳性。
    结论 本次疫情为老年福利院报告的一起诺如病毒引起的暴发疫情,院内人员密切接触和护工健康带毒导致本次疫情暴发的可能性大。

     

    Abstract:
    Objective To investigate an outbreak of norovirus diarrhea in a welfare home for the elderly in Shanghai, and to analyze the epidemiology and virus genotype characteristics of the epidemic, thus providing a scientific basis for the prevention and control of norovirus epidemic.
    Methods Case definition was clarified. After case definition, a standardized questionnaire was used to carry out case investigation to make comprehensive analysis in combination with field epidemiological investigation and laboratory tests results.
    Results The epidemic lasted for 14 days, and 23 cases were reported with an incidence rate of 12.37% (23/186), including 3 males and 20 females. There were more cases on the 1st, 4th and 6th floor of the main building in the welfare home, accounting for 52.17% (12/23) of total cases. 19 cases were reported in the main building, with an incidence rate of 11.59% (19/164); 4 cases were reported in the auxiliary building, with an incidence rate of 18.18% (4/22). There was no significant difference in the morbidity between the main building and the auxiliary building (χ2=0.779,P>0.05). The main clinical manifestations were vomiting and diarrhea. There was a significant difference in the incidence of vomiting symptoms among the elderly, nursing staff and other staff in the welfare home (χ2=10.216, P<0.05). But there was no significant difference in the incidence of diarrhea among the elderly, nursing staff and other staff (χ2=1.218, P>0.05). Fecal samples were collected from 23 cases, 1 case family member, 68 risk personnel and 14 environmental surface swab samples. Norovirus GⅡ was detected in stool samples of 19 cases, 1 family member and 36 risk personnel.
    Conclusion Outbreak of norovirus infection is reported in a welfare home in Shanghai. The close contact between the elderly and health workers might lead to the outbreak.

     

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