青海省成年女性人乳头状瘤病毒疫苗接种意愿及影响因素分析

Analyses of human papilloma virus vaccination willingness and its influencing factors among adult women in Qinghai Province

  • 摘要:
    目的 分析青海省成年女性人乳头状瘤病毒(HPV)疫苗接种意愿及影响因素,为制定更具针对性的健康干预策略提供科学依据。
    方法 采用多阶段整群随机抽样的方法,于2024年12月—2025年1月在青海省8个市(州),开展人乳头瘤病毒疫苗接种意愿的问卷调查,采用层次多元回归分析接种意愿的影响因素。
    结果 923名调查者的结果显示,成年女性HPV疫苗接种意愿得分在文化程度 (F=9.596,P<0.001)和职业(F=8.494,P<0.001)因素中差异有统计学意义。根据层次多元回归模型结果发现,感知易感性(β=0.078,P<0.05)、行动线索(β=0.134,P<0.05)和主观规范(β=0.407,P<0.001)是成年女性接种HPV疫苗意愿的正向影响因素,感知障碍(β=-0.113,P<0.001)是成年女性接种HPV疫苗意愿的负向影响因素。
    结论 青海省成年女性接种HPV疫苗意愿受感知易感性、感知障碍、行动线索、主观规范的影响。提示政府和相关机构采取针对性策略,如优化健康教育、提升疫苗可及性、降低接种障碍,并强化社会支持体系,以提升HPV疫苗接种率,最终实现宫颈癌的有效防控和消除目标。

     

    Abstract:
    Objective To analyze the willingness to receive human papilloma virus (HPV) vaccine and its influencing factors among adult women in Qinghai Province, so as to provide scientific basis for the formulation of targeted health intervention strategies.
    Methods A multi-stage whole cluster random sampling method was used to conduct a questionnaire survey on the willingness to receive HPV vaccine in eight cities or states of Qinghai Province from December 2024 to January 2025. Hierarchical multiple regression analyses were used to identify the influencing factors associated with HPV vaccination willingness.
    Results The results of the 923 participants participated the questionnaire survey revealed that adult women’s HPV vaccination willingness scores differed statistically significant by educational level (F=9.596, P<0.001) and occupation (F=8.494, P<0.001). The hierarchical multiple regression modeling showed that perception of susceptibility (β=0.078, P<0.05), cues to action (β=0.134, P<0.05), and subjective norms (β = 0.407, P<0.001) were positively associated with HPV vaccination willingness among adult women, while perceptual disorder (β =-0.113, P<0.001) was negatively associated with it.
    Conclusion The willingness to receive HPV vaccine among adult women in Qinghai Province is influenced by perception of susceptibility, perceptual disorder, cues to action, and subjective norms. Policy makers and public health agencies should therefore adopt targeted strategies, such as optimizing health education, improving vaccine accessibility, lowering barriers to vaccination, and reinforcing supportive social networks, to increase HPV vaccine uptake and ultimately achieve the goal of effective prevention, control, and elimination of cervical cancer.

     

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