Abstract: Objective: Understand the improvement in the timeliness of infectious disease reporting through the implementation of smart monitoring and early warning front-end software in specialized hospitals, including the reduction in reporting deadlines.Methods: Select the infectious disease reporting data from the National Disease Prevention and Control System for January-July 2024 (pre-implementation) and January-July 2025 (post-implementation). Using descriptive epidemiological methods, compare and analyze the basic information, reporting timelines, and population composition of infectious disease patients between 2024 and 2025, categorized by different reporting methods, disease types, and demographic characteristics before and after the implementation.Results： The number of patients who visited our hospital for infectious diseases from January to July 2024 and January to July 2025 were 623 and 587, respectively. 596 cases, accounting for 49.26%, were reported within 10 hours before and after the implementation of intelligent monitoring and early warning software; The time period with the highest number of reported cases was from 1 hour to group (378 cases), accounting for 31.24%. There was a statistically significant difference in the reporting time before and after the implementation of the pre software (χ2=27.381, P < 0.05). The shortest reporting period from January to July 2025 has been shortened by 0.04 hours, the longest period by 0.55 hours, and the average period by 1.48 hours compared to January to July 2024. After implementation, the reporting deadline for Saturdays, Sundays, and statutory holidays will be significantly shortened. Conclusion: After the implementation of intelligent monitoring and early warning pre software, the reporting time for infectious diseases has been significantly shortened. Therefore, reducing the reporting deadline for pre installed software has increased the timeliness and accuracy of infectious diseases, the implementation of this software provides a reference basis for the promotion and implementation of national front-end software in medical institutions.