王琴, 王顺红, 王娜, 赵琦, 张镕. 上海市佘山镇65岁及以上老年人肥胖与血糖水平关联的横断面研究[J]. 上海预防医学, 2021, 33(6): 509-513. DOI: 10.19428/j.cnki.sjpm.2021.19665
引用本文: 王琴, 王顺红, 王娜, 赵琦, 张镕. 上海市佘山镇65岁及以上老年人肥胖与血糖水平关联的横断面研究[J]. 上海预防医学, 2021, 33(6): 509-513. DOI: 10.19428/j.cnki.sjpm.2021.19665
WANG Qin, WANG Shun-hong, WANG Na, ZHAO Qi, ZHANG Rong. Cross-sectional study on the correlation between obesity and blood glucose level in elderly people over 65 years old in Sheshan Town[J]. Shanghai Journal of Preventive Medicine, 2021, 33(6): 509-513. DOI: 10.19428/j.cnki.sjpm.2021.19665
Citation: WANG Qin, WANG Shun-hong, WANG Na, ZHAO Qi, ZHANG Rong. Cross-sectional study on the correlation between obesity and blood glucose level in elderly people over 65 years old in Sheshan Town[J]. Shanghai Journal of Preventive Medicine, 2021, 33(6): 509-513. DOI: 10.19428/j.cnki.sjpm.2021.19665

上海市佘山镇65岁及以上老年人肥胖与血糖水平关联的横断面研究

Cross-sectional study on the correlation between obesity and blood glucose level in elderly people over 65 years old in Sheshan Town

  • 摘要:
    目的了解上海市佘山镇≥65岁未诊断为糖尿病的老年人中肥胖与空腹血糖水平之间的关联性。
    方法收集2018年度佘山镇老年人体检数据,包括体质量指数(BMI)、腰围(WC)、腰臀比(WHR)、腰高比(WHtR),排除曾被诊断为糖尿病的患者,空腹血糖水平采用己糖激酶法获得。采用卡方检验比较不同肥胖状况不同性别空腹血糖水平,并采用logistic回归分析探讨相关肥胖等级指标与是否患糖尿病情况间的关系。
    结果本研究共纳入4 434名研究对象,其中男性1 921人、女性2 513人,中位年龄71岁。研究对象的平均空腹血糖水平为(5.87±1.48)mmol/L,糖尿病患病率为11.9%(526/4 434)。在不同肥胖相关指标中,BMI、WC、WHtR及WHR与空腹血糖水平的相关系数分别为0.149、0.125、0.21及0.075(均P <0.001);多因素logistic回归分析发现,老年人糖尿病风险随着WC、WHR及WHtR的肥胖程度上升,而在进一步调整腰围后,BMI与糖尿病患病之间的关联差异无统计学意义。
    结论老年人糖尿病的发病可能与肥胖相关,尤其与向心性肥胖关系密切,通过建立适合的回归模型可以预测糖尿病的发病,为疾病的防治提供科学可靠的依据。

     

    Abstract:
    ObjectiveTo investigate the relationship between obesity and fasting blood glucose levels in elderly people over 65 years old without diabetes mellitus in Sheshan Town.
    MethodsThe physical examination data of the elderly in Sheshan Town in 2018 were collected, including body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR). Patients who had been diagnosed with diabetes were excluded. Fasting blood glucose level was determined by glucokinase method. Chi-square test was used to compare the fasting blood glucose levels in men and women with different obesity status. Logistic regression analysis was used to explore the relationship between obesity-related indicators and diabetes mellitus.
    ResultsA total of 4 434 subjects were included in this study, including 1 921 males and 2 513 females, with a median age of 71 years. The average fasting blood sugar level was (5.87±1.48)mmol/L and the prevalence of diabetes was 11.9% (526/4 434). The correlation coefficients of BMI, WC, WHtR and WHR with fasting blood glucose level were 0.149, 0.125, 0.21 and 0.075 (P<0.001), respectively. Multivariate logistic regression analysis showed that the risk of diabetes in the elderly increased with the obesity of WC, WHR and WHtR. BMI and WHtR were significantly higher in the elderly, but after further adjusting by waist circumference, they were not significantly correlated with diabetes mellitus.
    ConclusionThe incidence of diabetes mellitus in the elderly may be related to obesity, especially centripetal obesity. Establishing a suitable regression model can predict the incidence of diabetes mellitus and provide a scientific and reliable basis for the prevention and treatment of the disease.

     

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