老年胃癌患者术后近期生存质量的研究

A study on the assessment of early postoperative quality of life in elderly gastric cancer patients

  • 摘要: 目的评估胃癌患者术后生存质量并探讨年龄对生存质量的影响。方法将135例胃癌患者随机分为老年组(≥ 60岁)和非老年组(<60岁),于确诊并行胃癌根治术后7 d用生存质量问卷(EORTC QLQ-C30)比较其差异。结果老年组术后住院时间长于非老年组(P<0.05);术后肺部感染和伤口感染的发生率高于非老年组(P<0.05)。QLQ-C30评分,功能子量表的躯体功能得分老年组低于非老年组(P<0.05);角色功能、情绪功能得分老年组高于非老年组(P<0.05)。症状子量表中的疼痛症状得分老年组低于非老年组(P<0.05)。其他测量项目的睡眠困难得分老年组高于非老年组(P<0.05)。总体健康子量表得分老年组高于非老年组(P<0.05)。结论老年胃癌患者术后生存质量总体上较非老年患者更高,但在躯体功能、睡眠等方面生存质量较低,应在围手术期采取针对性的措施。

     

    Abstract: Objective To assess early postoperative quality of life in gastric cancer patients and discuss the influence of old age on that.Methods A group of 135 patients were randomly divided into elderly group(aged ≥ 60) and non-elderly group(aged< 60), who were diagnosed with gastric cancer and received radical gastrectomy. Postoperatively 7 days, assessment and comparison were made between the two groups by means of the questionnaire QLQ-C30 of Chinese version. Results The incidence of postoperative complication of pulmonary infection and wound infection were higher in elderly group(P<0.05). In QLQ-C30 assessment, the physical function score of functional subscale in elderly group was lower than that in non-elderly group (P<0.05). Role function and cognitive function scores of functional subscale in elderly group were higher (P<0.05). Pain score of symptom subscale in elderly group was lower (P<0.05). Other items as sleep disturbance were higher in elderly than in non-elderly group (P<0.05). Overall health subscale score was higher in elderly group than in non-elderly group(P<0.05). Conclusion Postoperative quality of life in elderly patients with gastric carcinoma was generally higher than that in non-elderly patients, but physical function and sleep disturbance quality were lower in elderly patients. So targeted measures should be taken in the peri-operative period in this regard.

     

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