Objective To analyze the infection status and epidemic characteristics of Vibrio parahaemolyticus diarrhea cases in Shanghai in recent years， and to explore its influencing factors and provide a basis for the prevention and control of Vibrio parahaemolyticus infection.

Methods Food-borne disease surveillance data in Shanghai from 2017 to 2018 was collected， and the infection status and epidemic characteristics of Vibrio parahaemolyticus were analyzed. χ² test and multivariate unconditional logistic regression were used to analyze the factors of Vibrio parahaemolyticus infection.

Results Among the food-borne surveillance cases in Shanghai from 2017 to 2018， the positive detection rate of Vibrio parahaemolyticus reached 5.1%， and the positive cases were concentrated in July， August， and September. Those working in the catering industry， migrant workers and workers， and the young and middle-aged people （19‒59 years old） have a high incidence. The results of multivariate analysis showed that dining in Qingpu， Songjiang or Minhang District， occupations of migrant workers and workers， age over 19 years old， the third quarter of a year， and the consumption of aquatic animals and related foods are risk factors for Vibrio parahaemolyticus infection.

Conclusion The infection of Vibrio parahaemolyticus in Shanghai is still one of the food-borne diseases that warrant our attention. Strengthening food safety management and supervision， and promoting publicity and education for key populations are important for reducing the risk of infection by this pathogen. At the same time， long-term monitoring of infectious diarrhea cases in this city is necessary to dynamically understand the infection and epidemic characteristics of Vibrio parahaemolyticus， and adjust the annual prevention and control measures in time.