Abstract: Objective To investigate the epidemiological characteristics of measles in Wuxi, in recent two years. Methods Measles cases data in the National Information System for Disease Surveillance and the National Information System for measles from 2009 to 2010 were analyzed using Excel 2003. Results From 2009 to 2010, a total of 515 measles cases were reported in Wuxi. The peak of incidence was noted from March to May every year. Children younger than 5 years old and people older than 20 years old were the major group affected by measles. Those who had no immunization history and whose immunization history remained unknown accounted for 56.70% and 31.65%. Conclusion An important factor resulting in measles attack is the lacking of adequate immunization for appropriate age groups in the area. Peaks of incidence rates were found in both younger infants and adults, indicating the need for further improvement in the coverage and timeliness of routine immunization of measles vaccines. Measures should be taken to control the incidence among migrant population and adults.