Abstract: Objective To analyze the epidemiological characters and tendencies of measles by investigating its incidence among inhabitants in Changning District of Shanghai, in order to provide scientific basis for measles control and prevention. Methods Measles cases were collected in Changning District from 2008 to 2012 and epidemiological features were analyzed. Besides, vaccine inoculation status was investigated and data analyzed. Results The results showed that a total of 78 measles cases were reported in Changning District during 2008-2012.The annual average incidence of measles was 1.94/100 000.The incidence in floating population was higher than that in local residents. The high incidence period was from March to June. Disperse resident children, commercial workers and retired workers were the top three groups of people which had the highest incidence. The onset ages showed to be a bimodel pattern, appearing to move toward poles. The incidence ratio between man and woman are 1.05:1. Conclusion Control of measles in floating population should be focused on in Changning District and it is suggested that measles vaccination be done among women of child-bearing age and migrant workers.