吴晓虹, 章光明. 金华市2015—2016年疑似预防接种异常反应监测分析[J]. 上海预防医学, 2017, 29(9): 707-711. DOI: 10.19428/j.cnki.sjpm.2017.09.010
引用本文: 吴晓虹, 章光明. 金华市2015—2016年疑似预防接种异常反应监测分析[J]. 上海预防医学, 2017, 29(9): 707-711. DOI: 10.19428/j.cnki.sjpm.2017.09.010
Xiao-hong WU, Guang-ming ZHANG. Surveillance analysis on adverse events following immunization in Jinhua in 2015-2016[J]. Shanghai Journal of Preventive Medicine, 2017, 29(9): 707-711. DOI: 10.19428/j.cnki.sjpm.2017.09.010
Citation: Xiao-hong WU, Guang-ming ZHANG. Surveillance analysis on adverse events following immunization in Jinhua in 2015-2016[J]. Shanghai Journal of Preventive Medicine, 2017, 29(9): 707-711. DOI: 10.19428/j.cnki.sjpm.2017.09.010

金华市2015—2016年疑似预防接种异常反应监测分析

Surveillance analysis on adverse events following immunization in Jinhua in 2015-2016

  • 摘要:
    目的分析金华市2015—2016年疑似预防接种异常反应(AEFI)的监测结果。
    方法通过中国免疫规划信息管理系统,收集金华市2015—2016年报告的AEFI个案数据,采用描述流行病学方法进行分析。
    结果金华市2015—2016年报告AEFI共1 993例,估算报告发生率为34.45/10万,报告县和乡覆盖率均为100.00%,各项监测指标均达到国家监测方案的要求。报告病例男女性别比为1.30:1,1岁以下儿童占总报告数的42.50%,5—8月报告数较多。个案分类中一般反应占91.57%,异常反应占6.42%,报告发生率最高的疫苗为百白破IPV和Hib五联疫苗(166例,报告发生率280.90/10万),最低的疫苗为脊灰减毒疫苗(31例,报告发生率4.24/10万),异常反应中临床诊断以过敏性皮疹为主,97.49%的AEFI治愈。
    结论金华市2015—2016年AEFI监测敏感性高,但还应进一步加强对AEFI监测处置的培训,提高AEFI监测管理水平。

     

    Abstract:
    ObjectiveTo analyze the surveillance data on adverse event following immunization (AEFI) in Jihua, in 2015-2016.
    MethodsThe AEFI data in 2015 and 2016 were collected through EPI Information Management System of China, and analyzed by descriptive epidemiological method.
    ResultsA total of 1993 AEFI cases during 2015-2016 were reported. The estimated incidence rate was 34.45 per 100, 000 doses, which covered all counties and townships in Jinhua. All surveillance indicators met the requirements in terms of National Surveillance Plan. The ratio of male and female cases was 1.30:1. And 42.50% cases were ≤1 years old and more cases were reported between May and August. In case classification, 91.57% of AEFI were as common and minor reaction cases, and 6.42% were abnormal reaction cases. The highest incidence rate of AEFI cases was caused by DTaP-IPV-Hib vaccine (166 cases, 280.90 per 100, 000 doses), and the lowest rate by oral polio vaccine (31 cases, 4.24 per 100, 000 doses). Allergic rash cases accounted for most of the abnormal reaction cases based on clinical diagnosis. 97.49% of AEFI cases were cured.
    ConclusionThe AEFI surveillance is highly sensitive in Jinhua in 2015 and 2016. Nevertheless, training on AEFI surveillance and response should be further strengthened, so as to further improve management level of AEFI surveillance.

     

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