Abstract: Objective The "2030 Plan for Healthy Shanghai" defines the goals and tasks of healthy Shanghai construction, which provides new opportunities and new requirements for the development of disease prevention and control institutions. Disease prevention and control institutions should be leader in healthy living, main force in health service, promoter in health security, guardian for healthy environment and participant in health industry.At the same time, they ought to grasp the new trend in the development of preventive medicine, then promoting preventive medicine plus internet, plus precision medicine, plus commercial health insurance and plus social multi-component governance.