鲍燕, 沈冰, 宁镇, 郭亚文, 杨芸, 王海涛, 葛梅华, 顾凯侃. 男男性传播HIV感染者对早期抗病毒治疗的可接受性及影响因素研究[J]. 上海预防医学, 2018, 30(3): 217-222. DOI: 10.19428/j.cnki.sjpm.2018.18481
引用本文: 鲍燕, 沈冰, 宁镇, 郭亚文, 杨芸, 王海涛, 葛梅华, 顾凯侃. 男男性传播HIV感染者对早期抗病毒治疗的可接受性及影响因素研究[J]. 上海预防医学, 2018, 30(3): 217-222. DOI: 10.19428/j.cnki.sjpm.2018.18481
Yan BAO, Bing SHEN, Zhen NING, Ya-wen GUO, Yun YANG, Hai-tao WANG, Mei-hua GE, Kai-kan GU. HIV-positive men who have sex with men:their acceptability of early antiretroviral treatment and its influencing factors[J]. Shanghai Journal of Preventive Medicine, 2018, 30(3): 217-222. DOI: 10.19428/j.cnki.sjpm.2018.18481
Citation: Yan BAO, Bing SHEN, Zhen NING, Ya-wen GUO, Yun YANG, Hai-tao WANG, Mei-hua GE, Kai-kan GU. HIV-positive men who have sex with men:their acceptability of early antiretroviral treatment and its influencing factors[J]. Shanghai Journal of Preventive Medicine, 2018, 30(3): 217-222. DOI: 10.19428/j.cnki.sjpm.2018.18481

男男性传播HIV感染者对早期抗病毒治疗的可接受性及影响因素研究

HIV-positive men who have sex with men:their acceptability of early antiretroviral treatment and its influencing factors

  • 摘要:
    目的探索男男性行为人群(MSM)中艾滋病病毒(HIV)感染者对早期抗病毒治疗的可接受性及其影响因素, 为推动上海市MSM人群治疗作为预防(TasP)策略实施提供依据。
    方法选择2015年1月—2017年6月上海市静安区新发现的、未开始治疗的且愿意配合开展流行病学调查的男男性传播HIV感染者共193例,采用自行设计的问卷,在知情同意的情况下,以面对面的方式进行问卷调查,内容包括人口学特征、艾滋病知识知晓情况、行为学特征、目前身体状况、抗病毒治疗知识、对早期抗病毒治疗的认知情况及接受意愿等。
    结果男男性传播HIV感染者对艾滋病早期抗病毒治疗政策的知晓率为14.5%,HIV感染者早期抗病毒治疗的接受率为82.4%。是否知晓早期抗病毒治疗的相关知识均与是否愿意接受早期抗病毒治疗显著相关(P值均 < 0.05)。多因素logistic回归分析结果显示,认为艾滋病目前可以治愈(OR=4.60,95%CI:1.45~14.61)、认为早期抗病毒治疗可以延缓发病(OR=4.58,95%CI:1.11~18.94)和认为可以预防性伴/配偶被感染(OR=3.56,95%CI:1.29~9.78)的HIV感染者更倾向于接受早期抗病毒治疗。
    结论上海市男男性传播HIV感染者对早期抗病毒治疗可接受性较高,但对早期抗病毒治疗政策的了解较少,应进一步加强MSM人群早期抗病毒治疗的动员和宣传,提高感染者对早期抗病毒治疗的全面认知,更好地促进TasP策略的实施, 进而预防HIV在MSM人群的传播。

     

    Abstract:
    ObjectiveTo investigate the acceptability of early antiretroviral therapy (ART) and its influencing factors among HIV-positive men who have sex with men (MSM) and to provide information for promoting the treatment as a preventive strategy in Shanghai.
    MethodsFrom January 2015 to June 2017, newly reported MSM infected with HIV were selected as research objects, and a total of 193 HIV-positive MSM who did not receive ART participated in the study.By means of self-designed questionnaire were collected general demographic information, awareness of AIDS knowledge, behavior characteristic, physical condition, cognition of early ART, acceptability of early ART etc.
    ResultsThe awareness rate for early ART was only 14.5% among HIV-positive MSM, and the rate of acceptability of early ART 82.4%.Univariate analysis showed that the factors significantly with acceptability of early ART were thinking HIV could be cured, worrying about medication compliance, thinking early ART could prevent partners from infection, believing that improving the survival rate of HIV, could delay the disease development, worrying others would suspect them of having HIV, thinking it was necessary to carry out early ART among MSM, all P < 0.05.Multivariate logistic regression analysis showed that the factors significantly with acceptability of early ART were thinking HIV could be cured(OR=4.60, 95%CI:1.45~14.61), thinking early ART could delay the disease development(OR=4.58, 95%CI:1.11~18.94), and thinking early ART could prevent partners from infection(OR=3.56, 95%CI:1.29~9.78).
    ConclusionThe rate of acceptability of early ART among HIV-positive MSM is high in Shanghai, but as the awareness rate for early ART is relatively low, we should strengthen the mobilization and publicity of early ART, improve the cognition of early ART among HIV-positive MSM, and promote the treatment as a preventive strategy, which will help reduce HIV spreading.

     

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