Abstract:
ObjectiveTo investigate the epidemiological characteristics of suspected new cases of acute hepatitis B in Suzhou City from 2015 to 2016.
MethodsFrom 2015 to 2016, the suspected new cases of acute hepatitis B reported by the direct network reporting system in the medical institutions in Suzhou were selected as the study subjects.All of them were administered interview using a standard questionnaire and their blood samples were collected.Data was obtained on demographic characteristics, immunization history of hepatitis B, history of liver diseases, risk factors within half a year and so on.Alanine transaminase (ALT) and anti-HBc IgM were tested for all participants.
ResultsA total of 325 patients with acute or unclassified hepatitis B were include in the final analysis, of whom 256 were male and 69 female, the sex ratio of male and female being 3.71:1. The average age of patients was 40.00±14.15 (Min 3 and Max 82 years old).Most people′s education level was junior high school.Many patients were unemployed persons and farmers.The positive rate of anti -HBc IgM 1:1000 was 78.77%.Compared to those with anti-HBc IgM 1:1000 (-), people with anti-HBc-IgM 1:1000 (+) had higher proportion of living in towns (P < 0.05).The proportion of patients having symptoms of hepatitis B was significantly higher for the people with anti-HBc IgM 1:1000 (+) than that for the people with anti-HBc IgM 1:1000 (-) (P < 0.05).Patients with anti-HBc IgM 1:1000 (+) had higher ALT than those with anti-HBc IgM 1:1000 (-) (P < 0.01).
ConclusionAs far as the acute hepatitis B patients are concerned, the proportion of males is higher than that of females in Suzhou City.Patients with anti-HBc IgM 1:1000 (+) always had symptoms of hepatitis B and higher ALT.Medical personnel should use epidemiological and laboratory tests for hepatitis B classification diagnosis so as to improve reporting accuracy.