许红梅, 张亮. 2017年上海某三级综合中医医院住院患者细菌感染及耐药性分析[J]. 上海预防医学, 2019, 31(3): 220-223. DOI: 10.19428/j.cnki.sjpm.2019.19023
引用本文: 许红梅, 张亮. 2017年上海某三级综合中医医院住院患者细菌感染及耐药性分析[J]. 上海预防医学, 2019, 31(3): 220-223. DOI: 10.19428/j.cnki.sjpm.2019.19023
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XU Hong-mei, ZHANG Liang. Bacterial distribution and their drug resistance surveillance at a class A general TCM hospital of Shanghai in 2017[J]. Shanghai Journal of Preventive Medicine, 2019, 31(3): 220-223. DOI: 10.19428/j.cnki.sjpm.2019.19023
Citation: XU Hong-mei, ZHANG Liang. Bacterial distribution and their drug resistance surveillance at a class A general TCM hospital of Shanghai in 2017[J]. Shanghai Journal of Preventive Medicine, 2019, 31(3): 220-223. DOI: 10.19428/j.cnki.sjpm.2019.19023
shu

2017年上海某三级综合中医医院住院患者细菌感染及耐药性分析

Bacterial distribution and their drug resistance surveillance at a class A general TCM hospital of Shanghai in 2017

    摘要
  • 摘要:
    目的了解2017年上海某三级综合中医医院住院患者的细菌感染及耐药情况，为临床合理选用抗菌药物提供依据。
    方法对2017年住院患者的临床标本进行药敏试验，药敏试验采用纸片扩散法，按美国临床和实验室标准协会(CLSI)2016标准判读结果。
    结果2017年共分离出1 547株细菌，其中革兰阴性菌1 222株，占79.0%；革兰阳性菌325株，占21.0%。检出细菌数居前5位的分别为大肠埃希菌(占22.2%)、肺炎克雷伯菌(占16.7%)、铜绿假单胞菌(占12.5%)、金黄色葡萄球菌(占12.3%)及鲍曼不动杆菌(占5.4%)。鲍曼不动杆菌对碳青霉烯类的耐药率较高，未发现对万古霉素、利奈唑胺、替加西林耐药的金黄色葡萄球菌。
    结论实时监测医院内细菌耐药的变化情况，可以科学指导临床使用抗菌药物并降低细菌耐药率。

     

    Abstract:
    ObjectiveTo investigate the distribution of conditioned pathogenic bacteria and their resistance to anti-bacterial drugs at a class A TCM(traditional chinese medicine) hospital in 2017 in order to provide a reference for the prevention and control of hospital infection and clinically rational selection of anti-bacterial drugs.
    MethodsThe drug sensitivity test was carried out by paper diffusion method, and the results were read according to the standard of CLSI 2016.
    ResultsA total of 1 547 clinical isolates were collected, of which the top 5 pathogenic bacteria were Escherichia coli(22.2%), Klebsiella pneumonia(16.7%), Pseudomonas aeruginosa(12.5%), Staphylococcus aureus(12.3%) and Acinetobacter baumannii (5.4%). The resistance rate of Acinetobacter bauman to carbapenems was higher. No Staphylococcus aureus was found to be resistant to vancomycin, linezolid and tegocycline.
    ConclusionDynamic monitoring of bacterial resistance changes in the region has important significance for guiding the rational selection of anti-bacterials and reducing the rate of bacterial resistance.

     

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