不同海拔地区体检人群空腹血糖水平的比较分析

仇燕; 关国跃; 许柏青; 费苛; 仲怀琴

doi:10.19428/j.cnki.sjpm.2019.19113

不同海拔地区体检人群空腹血糖水平的比较分析

Comparison and analysis of fasting blood glucose at different altitude areas in physical examination population

摘要

摘要:
目的对比高原地区与平原地区健康体检人群空腹血糖水平差异，以进一步探讨血糖的影响因素。
方法回顾性从我院2014年至2017年健康体检数据中，随机选取389例青海果洛藏族自治州与548例上海金山区健康体检人群作为研究对象，采集研究对象的性别、年龄、民族、空腹血糖、腰围、体质指数、空腹胰岛素等相关数据进行对比分析，运用Logistic回归分析空腹血糖升高的相关因素。
结果与平原地区比较，高原地区空腹血糖明显偏低，而腰围(85.25 vs 89.98)、BMI(25.48 vs 26.98)、空腹胰岛素水平(51.72 vs 62.82)、血尿酸明显偏高(344.75 vs 403.48)。回归分析筛选出四个相关因素：高原、年龄、腰围、空腹胰岛素。
结论高海拔地区人群较平原地区空腹血糖明显偏低。高原、年龄、腰围、空腹胰岛素水平均是空腹血糖影响因素。体质指数与空腹血糖升高无明显相关性。

Abstract:
ObjectiveTo compare the difference of fasting blood glucose(FBG) levels between healthy people living in plateau and plain areas so as to further explore the influencing factors of blood glucose.
MethodsThree hundred and eighty nine subjects from Guoluo Region of Qinghai and 548 subjects from physical examination in Jinshan District of Shanghai were randomly selected.By t-test and Chi-square(χ²) test were compared the differences of age, nationalities, FBG, fasting insulin, waist circumference, body mass index between the highland group and plains group.By Logistic regressions, the influencing factors were analyzed for elevated FBG.
ResultsFBG levels of people living in highland were lower than those living in plain areas.The levels of fasting insulin, waist circumference, body mass index and blood uric acid were higher in highland(all P < 0.05).The results of logistic regressions demonstrated that four factors were related to FBG elevation, including highland, age, waist circumference and fasting insulin(all P < 0.05).
ConclusionFBG of people living in highland areas are lower than that of those in plain areas.It is proved that highland, age, waist circumference and fasting insulin are associated with FBG.There was no significant relationship found between body mass index and FBG.

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