上海市浦东新区小学水痘聚集性疫情首发病例影响因素分析

沈奕峰; 郭绍华; 孔令飞; 王琦璋; 文京海; 丁王静

doi:10.19428/j.cnki.sjpm.2020.19585

上海市浦东新区小学水痘聚集性疫情首发病例影响因素分析

Influencing factors for first cases of varicella aggregation outbreaks in primary school in Pudong New Area of Shanghai

摘要

摘要:
目的了解上海市浦东新区小学水痘聚集性疫情首发病例影响因素，为有效开展水痘防控工作提供依据。
方法抽取浦东新区80起小学水痘聚集性疫情首发病例，采用病例对照研究方法，收集病例及对照的免疫史、外出活动史、校外培训等资料，进行单因素、多因素条件logistic回归分析。
结果多因素分析显示：水痘疫苗接种年限(OR=0.08，95%CI：0.01~0.44)是聚集性疫情首发病例的保护因素；每周去大型商业/超市频次(OR=4.79，95%CI：1.86~12.34)、每周参加校外培训频次(OR=1.84，95%CI：1.01~3.35)是聚集性疫情首发病例的危险因素。
结论推行好现行水痘疫苗免疫策略，加强大型商业/超市的消毒和健康教育工作，加强校外培训机构的传染病管理和防病指导督导, 对聚集性水痘疫情防控具有现实意义。

Abstract:
ObjectiveTo investigate influencing factors of the first cases of varicella outbreaks in primary school in Pudong New Area of Shanghai and to provide scientific evidence for effective prevention and control measures against it.
MethodsThe first 80 cases of varicella outbreaks in primary school in Pudong New Area were included for the case-control study.Immunization history, outing activities and information of out-of-school training were gathered.Univariate and multivariate conditional logistic regression analysis were adopted for data analysis.
ResultsMultivariate analysis revealed that varicella vaccination period(OR=0.08, 95%CI:0.01-0.44)was the protective factor for the first case in a varicella outbreak, while weekly frequency of visits to large commercial/supermarkets (OR=4.79, 95%CI:1.86-12.34)and weekly attendance at out-of-school training(OR=1.84, 95%CI:1.01-3.35)were risk factors of the disease.
ConclusionIt is important to promote the current varicella vaccine immunization strategy, to strengthen the disinfection and health education of large commercial/supermarkets and to strengthen infectious disease management, disease prevention guidance and supervision in out-of-school training institutions.

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