马小敏, 王芳, 李淑华, 曹广文. 上海市金山区健康体检人群麻疹抗体水平监测结果分析[J]. 上海预防医学, 2020, 32(4): 320-324, 328. DOI: 10.19428/j.cnki.sjpm.2020.19921
引用本文: 马小敏, 王芳, 李淑华, 曹广文. 上海市金山区健康体检人群麻疹抗体水平监测结果分析[J]. 上海预防医学, 2020, 32(4): 320-324, 328. DOI: 10.19428/j.cnki.sjpm.2020.19921
MA Xiao-min, WANG Fang, LI Shu-hua, CAO Guang-wen. Surveillance of the levels of measles antibody in physical examination population in Jinshan District, Shanghai[J]. Shanghai Journal of Preventive Medicine, 2020, 32(4): 320-324, 328. DOI: 10.19428/j.cnki.sjpm.2020.19921
Citation: MA Xiao-min, WANG Fang, LI Shu-hua, CAO Guang-wen. Surveillance of the levels of measles antibody in physical examination population in Jinshan District, Shanghai[J]. Shanghai Journal of Preventive Medicine, 2020, 32(4): 320-324, 328. DOI: 10.19428/j.cnki.sjpm.2020.19921

上海市金山区健康体检人群麻疹抗体水平监测结果分析

Surveillance of the levels of measles antibody in physical examination population in Jinshan District, Shanghai

  • 摘要:
    目的了解金山区健康体检人群麻疹免疫水平,为金山区麻疹免疫防控提供依据。
    方法收集金山区常住人口15岁及以上的体检人群血清,采用酶联免疫吸附实验(ELISA)检测麻疹IgG抗体浓度,采用统计学方法进行比较分析。
    结果金山区15岁及以上体检人群麻疹抗体阳性率为70.74%,抗体保护率为17.56%。麻疹抗体分布在不同性别、本市户籍与外来人口之间差异均无统计学意义(P>0.05),不同年龄组之间麻疹抗体阳性率差异无统计学意义(P>0.05),但保护率分布有统计学意义(χ2=44.53,P < 0.05),本市户籍与外来人口抗体水平分布差异无统计学意义(P>0.05), 15~24岁年龄组麻疹抗体保护率最低,仅为9.60%,随年龄增长抗体保护率增高。65~95岁年龄组人群麻疹抗体保护率最高,为25.62%。
    结论金山区体检人群麻疹抗体免疫水平处于较低水平,存在麻疹暴发的潜在风险,尤其需重点加强本市户籍及外来人口15~24岁年龄组麻疹强化免疫工作,建议推广成人麻疹免疫接种计划。

     

    Abstract:
    ObjectiveTo investigate the level of measles antibody in physical examination population in Jinshan District, and provide evidence for measles immunization prevention and control in different populations.
    MethodsThe sera of physical examination population aged 15 years and older in Jinshan was collected.The titer of IgG antibody against measles was measured by using enzyme-linked immunosorbent assay (ELISA).Statistical methods were used to compare and analyze the data.
    ResultsThe overall positive rate of measles antibody in physical examination population aged 15 and older in Jinshan was 70.74%, and the antibody protection rate was 17.56%.There was no significant difference in the distribution of measles antibody between different genders, or local population and migrant population (P>0.05).There was no significant difference in the positive rate of measles antibodies between different age groups (P>0.05), but the protection rate was statistically significant(χ2=44.53, P < 0.05).There was no statistically significant difference in the distribution of antibody levels between residents and migrants in all age groups.The rate of measles antibody protection in the 15-24 age group was the lowest, only 9.60%, and the antibody protection rate increased with age.The rate of measles antibody protection in the 65-95 age group was the highest, 25.62%.
    ConclusionThe immunization level of measles antibody in physical examination population in Jinshan District is at a low level, and there is a potential risk of measles outbreak.In particular, it is imperative to focus on strengthening the measles immunization work in 15-24 age population.It is recommended to promote adult measles immunization program.

     

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