金纬娟, 张越, 张宏伟. 小于胎龄儿追赶生长情况及其与神经心理发育的关联性研究[J]. 上海预防医学, 2020, 32(6): 506-510. DOI: 10.19428/j.cnki.sjpm.2020.20048
引用本文: 金纬娟, 张越, 张宏伟. 小于胎龄儿追赶生长情况及其与神经心理发育的关联性研究[J]. 上海预防医学, 2020, 32(6): 506-510. DOI: 10.19428/j.cnki.sjpm.2020.20048
JIN Wei-juan, ZHANG Yue, ZHANG Hong-wei. Relationship between catch-up growth pattern and neuropsychological development in small-for-gestational-age(SGA) infants[J]. Shanghai Journal of Preventive Medicine, 2020, 32(6): 506-510. DOI: 10.19428/j.cnki.sjpm.2020.20048
Citation: JIN Wei-juan, ZHANG Yue, ZHANG Hong-wei. Relationship between catch-up growth pattern and neuropsychological development in small-for-gestational-age(SGA) infants[J]. Shanghai Journal of Preventive Medicine, 2020, 32(6): 506-510. DOI: 10.19428/j.cnki.sjpm.2020.20048

小于胎龄儿追赶生长情况及其与神经心理发育的关联性研究

Relationship between catch-up growth pattern and neuropsychological development in small-for-gestational-age(SGA) infants

  • 摘要:
    目的了解小于胎龄儿(SGA)2周岁时体格发育的追赶情况及神经心理发育情况,并探索两者间的关系。
    方法对出生日期为2016年1月1日—2017年1月1日的185名SGA进行纵向随访观察,在24月龄时使用统一方法测量儿童身高、体重、头围等体格发育指标,并采用格塞尔(Gesell)发育量表对追赶生长与未追赶生长SGA儿童的神经心理发育情况进行评估分析。
    结果体格发育方面,185名SGA中有179名在2周岁时接受了体格发育检查,其中达到追赶生长的儿童占56.98%(102/179);在神经心理发育方面,虽然同样是SGA,但非上海市户籍儿童、足月SGA的神经心理发育可疑/异常检出率更高(P<0.05);在调整了户籍、孕周因素后,发现体格追赶生长组儿童的Gesell评估可疑/异常检出率低于未追赶生长组,但差异无统计学意义(P>0.05)。
    结论在SGA中,2周岁时体格发育未达到追赶生长的儿童,其神经心理发育落后不明显,追赶生长对于宫内发育迟缓的儿童主要表现在身高、体重追赶的积极意义,在促进神经心理方面发展的意义仍需进一步研究。

     

    Abstract:
    ObjectiveTo explore the relationship between the catch-up situation of physical development and neuropsychological development in 2-year-old SGA children.
    MethodsA longitudinal follow-up observation was conducted in 185 SGA children who were recruited between January 1, 2016 and January 1, 2017.The height, weight, head circumference and other physical development indicators were measured by unified methods at the age of 24 months.Gesell development scale was used to evaluate the neuropsychological development of catch-up and non-catch-up children.
    ResultsIn 179 out of 185 SGA children who received physical development examination 56.98%(102/179) had achieved catch-up growth.The rate of abnormal/suspected-abnormal neuropsychological development in the full-term SGA children without Shanghai household registration was higher(P < 0.05).After adjusting the factors of household registration and gestational age, there was no significant difference in neuropsychological development between the catch-up and non-catch-up children(P>0.05).
    ConclusionSGA children, whose physical development did not reach the catch-up growth at the age of 2 years are not obviously backward in neuropsychological development.Catch-up growth for the children with intrauterine growth retardation mainly shows the positive significance in height and weight.The significance of catch-up growth in neuropsychological development remains to be studied.

     

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