Abstract: Novel coronavirus pneumonia disease (COVID-19) caused by SARS-CoV-2 was identified in December 2019, and is gradually spreading globally including Japan.The COVID-19 case in Japan began to appear in middle January 2020 and continued to increase over time.The period from middle January to the end of February is considered to be the initial stage of domestic transmission in Japan.The paper descibes the spread of 935 cases of COVID-19 related to Japan by the end of February 2020, including the 15 infected Japanese returned from Wuhan, the 696 infected individuals in the large-scale cruise ship "Diamond Princess" and the 224 infected individuals in Japan.This paper summarizes the measures to control the spread of SARS-CoV-2 in Japan, such as limiting RT-PCR detection for SARS-CoV-2, reducing the number of patients with mild illness who go to medical institutions unnecessarily, formulating guidelines for SARS-CoV-2 infection consultation, canceling large gatherings and temporarily closing schools.This paper further points out the problems encountered in the prevention and control of the spread of SARS-CoV-2 in Japan, such as the slow detection of RT-PCR, the risk of infection faced by medical staff, the regional differences in the domestic health care service system, the confusion of information disclosure and management.The paper allows us to acquire a better understanding of the new coronavirus pneumonia in Japan and the world and may provide reference for the control the epidemic of COVID-19 in worldwide.