辽宁省盘锦市12例新型冠状病毒肺炎的临床转归分析

李环; 徐健峰; 孙晓丽; 姚启哲; 郭微; 齐红霞; 孙畅

doi:10.19428/j.cnki.sjpm.2020.20355

辽宁省盘锦市12例新型冠状病毒肺炎的临床转归分析

Prognosis analysis of 12 patients with COVID-19 in Panjin City, Liaoning Province

摘要

摘要:
目的分析辽宁省盘锦市12例新型冠状病毒肺炎(COVID-19)病例的发病特征、新型冠状病毒(SARS-CoV-2)核酸转阴时间，了解出院后核酸复阳的影响因素。
方法回顾性分析盘锦市12例COVID-19病例的临床表现、实验室检查及影像学检查，对病例SARS-CoV-2核酸转阴时间、核酸复阳情况进行相关性分析。
结果12例COVID-19病例临床症状以发热(9/12)及呼吸道症状(8/12)为主，淋巴细胞降低者4例，影像学诊断肺炎病例11例，2例病例出院1周内鼻咽/肛拭子SARS-CoV-2核酸检测再次阳性。病例核酸转阴时间8~53 d、中位时间24.5 d，分析相关因素中影像学提示肺炎、病例来源于就诊和复阳是影响因素。
结论COVID-19的临床转归个体差异较大、相关影响因素较多。应当引起足够的重视，防止疫情蔓延。

Abstract:
ObjectiveThe characteristics of coronavirus disease 2019 (COVID-19) were analyzed in 12 cases, including time of negative conversion of SARS-CoV-2 RNA and risk factors associated with testing re-positive for SARS-CoV-2 RNA after the discharge.
MethodsA total of 12 patients with COVID-19 in Panjin were collected.Clinical features, laboratory testing, and imaging examination of the patients were retrospectively studied.Moreover, the correlation between the time of negative conversion of SARS-CoV-2 RNA and testing re-positive after the discharge were determined.
ResultsThe clinical symptoms of 12 COVID-19 cases were mainly fever (9/12) and respiratory symptoms (8/12).In addition, there was lymphocyte reduction in 4 cases, imaging diagnosis of pneumonia in 11 cases, and 2 cases testing re-positive for SARS-CoV-2 RNA in the nasal pharyngeal/anal swab within 1 week of discharge.The time of negative conversion in the cases was 8-53 days, and the median time was 24.5 days.Imaging demonstrating the pneumonia, the case coming from the hospital visit, and testing re-positive for SARS-CoV-2 RNA were the risk factors.
ConclusionPrognosis and its risk factors vary in the influencing factors of COVID-19 cases.It warrants more attention to prevent the spread of COVID-19.

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