刘艳, 沈建勇, 闻栋, 刘光涛. 2011-2017年浙江省湖州市流感监测病原学分析[J]. 上海预防医学, 2021, 33(2): 115-119. DOI: 10.19428/j.cnki.sjpm.2021.19290
引用本文: 刘艳, 沈建勇, 闻栋, 刘光涛. 2011-2017年浙江省湖州市流感监测病原学分析[J]. 上海预防医学, 2021, 33(2): 115-119. DOI: 10.19428/j.cnki.sjpm.2021.19290
LIU Yan, SHEN Jian-yong, WEN Dong, LIU Guang-tao. Influenza surveillance in Huzhou during 2011-2017[J]. Shanghai Journal of Preventive Medicine, 2021, 33(2): 115-119. DOI: 10.19428/j.cnki.sjpm.2021.19290
Citation: LIU Yan, SHEN Jian-yong, WEN Dong, LIU Guang-tao. Influenza surveillance in Huzhou during 2011-2017[J]. Shanghai Journal of Preventive Medicine, 2021, 33(2): 115-119. DOI: 10.19428/j.cnki.sjpm.2021.19290

2011-2017年浙江省湖州市流感监测病原学分析

Influenza surveillance in Huzhou during 2011-2017

  • 摘要:
    目的了解浙江省湖州市2011-2017年流行性感冒(流感)流行特征,为流感防控提供科学依据。
    方法根据国家流感监测方案,在2家流感哨点监测医院的流感样病例(ILI)中随机抽取病例进行咽拭子采样的病原学监测。
    结果2011-2017年湖州市共计就诊病例5 322 788例,其中ILI为185 010例,占就诊人数百分比(ILI%)为3.48%,每月ILI%有缓慢上升趋势(趋势χ2 =2 970.928,P < 0.001)。ILI具有冬春季节和夏季两个高峰,病例主要集中在14岁及以下(占89.1%)人群中。检测ILI咽拭子11 490份,检出流感病毒阳性1 975株,阳性率为17.19%:其中A型H3N2 1 008株,甲型H1N1 350株,B型614份(Victoria型160株,B型Yamagata 238株,B型未分型216份),混合型3份。ILI%与核酸检测阳性率呈现正相关(r = 0.40,P < 0.001)。
    结论湖州市流感一年有冬春季和夏季两个流行高峰,以14岁以下青少年人群发病为主,病原以A型H3N2为主,间隔出现乙型和甲型H1N1流行,流感活动度与ILI%有正相关关系。

     

    Abstract:
    ObjectiveThe influenza monitoring results in Huzhou city were analyzed to understand the characteristics of influenza pandemic and to provide a scientific basis for prevention and control of influenza.
    MethodsThe influenza-like cases(ILI)were collected from two sentinel hospitals in Huzhou according to the protocol of The National Influenza Surveillance Program. Pharynx swab samples of the ILI were taken randomly for the test of influenza virus.
    ResultsAmong 5 322 788 patients who went to the sentinel hospitals in Huzhou from 2011 to 2017, 185 010 were ILI. The percentage of ILI was 3.48% and there was a slowly rising trend in ILI% of month from 2011 to 2017(trend χ2 = 2 970.93, P < 0.001). Winter /spring and summer seasons marked the peaks in influenza epidemics. Patients were mostly children under 14 years old(accounting for 89.1%). In a total of 11 490 throat swabs collected from ILI, 1 975 were tested to be positive for influenza virus(positive rate 17.19%). These included A type H3N2, 1 008; A type H1N1, 350; B type, 614(160 Victoria type, 238 Yamagata, 216 unclarified B type), and 3 mixed type. The correlation between positive rate of influenza nucleic acid test and ILI% is statistically significant(r = 0.40, P < 0.001).
    ConclusionThe incidence peaks of influenza in Huzhou are mainly in the winter /spring and summer periods. The influenza is mainly occurs in young people under 14 years old and the main type virus is A(H3N2). The prevalence of influenza B and H1N1 occurs at intervals. There is a positive correlation between influenza activity and ILI%.

     

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