Abstract: Planned immunization program in Jiading District has experienced nearly 70 years，and basically established a relatively complete vaccination service system. Vaccination clinics have experienced four rounds of construction，which facilitates scientific，standardized，and informationized clinics. Moreover， it has trained a great deal of public health professionals in immunization program. Vaccines are able to be ordered and distributed uniformly，achieved with cold-chain equipment and real-time monitoring of temperature. Through a networking of vaccination information system， five-code linkage， which means vaccine traceability code， vaccine producing code，cold-chain equipment code，vaccinated child code，and vaccinating doctor code， has been achieved. Vaccines for expanded program immunization developed quickly， from 7 categories for preventing 8 diseases to 12 categories for preventing 13 diseases. In addition， number of self-funded vaccines are increasingly available. Currently， Jiading District is the first district implementing vaccination compensation insurance in Shanghai. Vaccine-preventable diseases are effectively controlled. However，challenges remain in the insufficient supply of self-funded vaccines and thorough elimination of measles.