夏曼曼, 姜永根, 郭晓芹. 20162017年上海市松江区成人哮喘患病现况及危险因素分析[J]. 上海预防医学, 2021, 33(11): 995-1000. DOI: 10.19428/j.cnki.sjpm.2021.20021
引用本文: 夏曼曼, 姜永根, 郭晓芹. 20162017年上海市松江区成人哮喘患病现况及危险因素分析[J]. 上海预防医学, 2021, 33(11): 995-1000. DOI: 10.19428/j.cnki.sjpm.2021.20021
XIA Man-man, JIANG Yong-gen, GUO Xiao-qin. Prevalence and risk factors of asthma among adults in Songjiang District of Shanghai: a cross-sectional study[J]. Shanghai Journal of Preventive Medicine, 2021, 33(11): 995-1000. DOI: 10.19428/j.cnki.sjpm.2021.20021
Citation: XIA Man-man, JIANG Yong-gen, GUO Xiao-qin. Prevalence and risk factors of asthma among adults in Songjiang District of Shanghai: a cross-sectional study[J]. Shanghai Journal of Preventive Medicine, 2021, 33(11): 995-1000. DOI: 10.19428/j.cnki.sjpm.2021.20021

20162017年上海市松江区成人哮喘患病现况及危险因素分析

Prevalence and risk factors of asthma among adults in Songjiang District of Shanghai: a cross-sectional study

  • 摘要:
    目的了解成人哮喘的患病现况及相关影响因素,为有针对性地预防和控制哮喘提供科学依据。
    方法采用多阶段分层整群抽样的方法,于2016—2017年在上海市松江区随机选取37 670名居民为调查对象,运用t检验和χ2检验比较组间差异,采用二元logistic回归模型探讨哮喘患病的影响因素。
    结果共纳入36 698名研究对象,752人自报有哮喘,患病率为2.05%;女性患病率为2.16%,男性患病率为1.88%,差异无统计学意义(P>0.05)。哮喘患者平均年龄高于非哮喘人群,分别为(60.3±9.48)岁和(56.29±11.31)岁,不同年龄的哮喘患病差异有统计学意义(P<0.05)。与非哮喘人群相比,哮喘患者更多是丧偶者(6.91%>4.45%,P<0.05),小学以下文化水平(58.64%>46.55%,P<0.01),且血清总胆固醇(TC)和低密度脂蛋白胆固醇(LDL-C)平均水平偏高(P<0.05)。在合并症方面,与非哮喘人群比较,哮喘患者更易伴有高血压史(42.00%>15.00%,P<0.001)、慢性支气管炎(51.33%>6.32%,P<0.001)、慢性阻塞性肺疾病(COPD) (6.25%>0.41%,P<0.001)、肺结核(2.66%>0.96%,P<0.05)、抑郁症(2.13%>0.41%,P<0.05)、帕金森病(0.93%>0.39%, P<0.05)。多因素logistic回归分析结果显示,抑郁症、慢性支气管炎、COPD、高血压史、家族史、高LDL-C水平和小学以下文化水平是哮喘患病的主要影响因素(P<0.05)。
    结论松江区成人哮喘患病率处于较高水平,应加强宣传教育,提高成人对哮喘危险因素的认知,改善成人哮喘的患病水平,从而减轻哮喘的负担。

     

    Abstract:
    ObjectiveTo determine the prevalence and risk factors of asthma among adults.
    MethodsA total of 37 670 adults aged 18 years and above was enrolled in Songjiang District, Shanghai using a multi-stage stratified sampling method between April 2016 and October 2017. Statistical analysis, such as t-test and Chi-square test, was performed to check the difference between the participants with asthma and non-asthma participants. Risk factors for asthma were examined by logistic regression analysis in all participants.
    ResultsOverall, 36 698 subjects were enrolled in the study, in which 752 had asthma. The overall prevalence of asthma was determined to be 2.05%. The prevalence in females was 2.16%, and that in males was 1.88%, which didn’t achieve significance(P>0.05). Compared to non-asthma participants, those with asthma were more likely to be older ([60.3±9.48] years vs. [56.29±11.31] years), widowed (6.91%>4.45%,P<0.05), with educational level of primary school and below (58.64%>46.55%, P<0.01), higher level of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) (P<0.05), had more co-morbidities, such as hypertension (42.00%>15.00%,P<0.001), chronic obstructive pulmonary disease (COPD) (6.25%>0.41%,P<0.001), chronic bronchitis (51.33%>6.32%,P<0.001) and tuberculosis (2.66%>0.96%,P<0.05), depression(2.13%>0.41%,P<0.05), and Parkinson's disease (0.93%>0.39%,P<0.05). Multivariable analysis showed that family history of asthma, history of hypertension, chronic bronchitis, COPD, depression and educational level of primary school and below were the risks factors associated with adult asthma (P<0.05).
    ConclusionPrevalence of adult asthma in Shanghai has increased in recent years. Targeted health education may be strengthened for improving adult awareness towards asthma and reducing the disease burden.

     

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