刘晶华, 刘萍, 刘敏. 中期妊娠合并新型冠状病毒肺炎2例报道[J]. 上海预防医学, 2021, 33(9): 791-794. DOI: 10.19428/j.cnki.sjpm.2021.20348
引用本文: 刘晶华, 刘萍, 刘敏. 中期妊娠合并新型冠状病毒肺炎2例报道[J]. 上海预防医学, 2021, 33(9): 791-794. DOI: 10.19428/j.cnki.sjpm.2021.20348
LIU Jing-hua, LIU Ping, LIU Min. Report of two imported COVID-19 cases in mid-term pregnancy[J]. Shanghai Journal of Preventive Medicine, 2021, 33(9): 791-794. DOI: 10.19428/j.cnki.sjpm.2021.20348
Citation: LIU Jing-hua, LIU Ping, LIU Min. Report of two imported COVID-19 cases in mid-term pregnancy[J]. Shanghai Journal of Preventive Medicine, 2021, 33(9): 791-794. DOI: 10.19428/j.cnki.sjpm.2021.20348

中期妊娠合并新型冠状病毒肺炎2例报道

Report of two imported COVID-19 cases in mid-term pregnancy

  • 摘要:
    目的研究中期妊娠合并输入性新型冠状病毒肺炎(COVID-19)患者的临床特点。
    方法对2020年3—4月收治于上海市公共卫生临床中心的2例输入性COVID-19病例(均为孕妇)的临床表现、辅助检查、治疗经过等进行回顾性分析。
    结果2例处于妊娠中期的COVID-19患者均为境外输入病例。例1来自美国,无症状;例2来自俄罗斯,有发热、咽痛,少许咳嗽、咳痰,伴有味觉及嗅觉减退症状。入院时的实验室检查结果提示例1白蛋白降低;例2的淋巴细胞计数及百分比降低,C反应蛋白、降钙素原增高,白蛋白降低,血清肌钙蛋白增高,但心电图无异常。2例孕妇肺部CT提示肺部均有病灶。例2因痰培养异常,给予头孢克洛口服。例1和例2分别住院14 d和12 d,2次咽拭子及粪便核酸检测转阴后出院。
    结论中期妊娠合并COVID⁃19的普通型患者治疗应以加强孕期监护为主,合理营养支持,适当心理干预,但妊娠结局需进一步随访。

     

    Abstract:
    ObjectiveTo study the clinical characteristics of imported coronavirus disease 2019 (COVID-19) cases in pregnancy.
    MethodsTwo imported COVID-19 cases in pregnancy admitted to Shanghai public health clinical center from March 2020 to April 2020 were retrospectively analyzed.
    ResultsThe two COVID-19 patients were in the second trimester of pregnancy, and were imported cases: case 1 came from the United States and was asymptomatic; case 2 came from Russia, and had fever, sore throat, cough and expectoration, and taste and smell loss. Laboratory testing on admission suggested that the albumin decreased in case 1. In case 2, lymphocyte count and percentage decreased, C-reactive protein and procalcitonin increased, albumin decreased, serum troponin increased, while the electrocardiogram was normal. Chest CT scans of the two cases were abnormal. They were administered with intensive care and nutritional support. Case 2 was treated with cefaclor tablets for 5 days. Case 1 and case 2 were hospitalized for 14 days and 12 days, respectively. They were discharged until twice nasopharyngeal swabs and fecal specimen tested negative for the novel coronavirus nucleic acid.
    ConclusionThe treatment for the patients with normal type of COVID-19 in the second trimester of pregnancy is aimed to strengthen the monitoring during pregnancy, which needs nutritional and psychological intervention. However, follow-up of pregnancy outcome is warranted .

     

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