张紫嫣, 郑亮, 刘昕雯, 周治彤, 李觉. 中国认知障碍患者与心力衰竭发病关系的meta分析[J]. 上海预防医学, 2021, 33(4): 327-334. DOI: 10.19428/j.cnki.sjpm.2021.20375
引用本文: 张紫嫣, 郑亮, 刘昕雯, 周治彤, 李觉. 中国认知障碍患者与心力衰竭发病关系的meta分析[J]. 上海预防医学, 2021, 33(4): 327-334. DOI: 10.19428/j.cnki.sjpm.2021.20375
shu
ZHANG Zi-yan, ZHENG Liang, LIU Xin-wen, ZHOU Zhi-tong, LI Jue. Prevalence of heart failure in Chinese cognitive impairment patients： a meta-analysis[J]. Shanghai Journal of Preventive Medicine, 2021, 33(4): 327-334. DOI: 10.19428/j.cnki.sjpm.2021.20375
Citation: ZHANG Zi-yan, ZHENG Liang, LIU Xin-wen, ZHOU Zhi-tong, LI Jue. Prevalence of heart failure in Chinese cognitive impairment patients： a meta-analysis[J]. Shanghai Journal of Preventive Medicine, 2021, 33(4): 327-334. DOI: 10.19428/j.cnki.sjpm.2021.20375
shu

中国认知障碍患者与心力衰竭发病关系的meta分析

Prevalence of heart failure in Chinese cognitive impairment patients： a meta-analysis

    摘要
  • 摘要:
    目的心力衰竭（心衰）和认知障碍已成为我国负担严重的医疗问题，本研究运用meta分析综合评价中国心力衰竭患者认知障碍的患病情况，为该人群的认知障碍干预和防治提供参考依据。
    方法检索1980年1月1日至2020年7月10日中国知网数据库、万方数据库、中国生物医学文献服务系统、维普中文科技期刊数据库、PubMed数据库中有关中国心力衰竭患者认知障碍患病相关研究文献。根据Agency for Healthcare Research and Quality（AHRQ）和Newcastle⁃Ottawa Scale（NOS）量表分别对纳入的横断面研究和病例对照研究进行文献质量评价，采用Stata16.0合并患病率及效应量。
    结果最终纳入20篇文献，文献均为中等质量。其中6篇为病例对照研究，总样本量为933人，以健康人群为对照，心衰与认知障碍的OR值为2.77（95%CI：2.05~3.74）。14篇为横断面研究，总样本量为3 000人，中国心衰患者认知障碍总患病率为54.3%（95%CI：0.43~0.65）。亚组分析显示，认知障碍患病率随心衰患者年龄的增大而升高，女性心衰患病率（58.4%）高于男性（48.4%），蒙特利尔认知评估量表筛选的患病率（63.6%）较简易精神状态检查量表（41.7%）高。
    结论中国心衰患者认知障碍患病率较高，且在年龄、性别等方面存在差异，应采取相应的措施及时防治和干预。

     

    Abstract:
    ObjectiveHeart failure （HF） and cognitive impairment have become serious medical problems in China. This study used meta-analysis to comprehensively evaluate the prevalence of cognitive impairment in patients with HF in China， and provided suggestions for intervention and prevention of cognitive impairment in this population.
    MethodsA systematic retrieval was conducted by searching relevant literatures regarding cognitive impairment in Chinese HF patients. These reports were published on CNKI， Wanfang， SinoMed， VIP and PubMed， from January 1， 1980 to July 10， 2020. The Agency for Healthcare Research and Quality （AHRQ） criteria and Newcastle-Ottawa Scale were used to evaluate the literature quality of cross-sectional studies and case-control studies， respectively. Stata16.0 was used for combined prevalence and effect value.
    ResultsA total of 20 articles with medium quality were included. Six of them were case-control studies， with a total sample size of 933 people， and healthy people as controls. The Odds Ratios （OR） value of the prevalence of cognitive impairment in patients with HF was 2.77 （95% CI： 2.05-3.74）. 14 articles were cross-sectional studies with a total sample size of 3000. In China， the prevalence of cognitive impairment in patients with HF was 54.3% （95% CI： 0.43-0.65）. Subgroup analysis showed that the prevalence of cognitive impairment was increased with age， and women had a higher prevalence （58.4%） than that in men （48.4%）. The prevalence in studies using the Montreal Cognitive Assessment （MoCA）to evaluate cognitive impairment （63.6%） was higher than those using Mini-mental State Examination （MMSE）（41.7%）. The limitations of this study include the following： only used the relevant literature on cognitive impairment in patients with HF in China； failed to explain the source of heterogeneity， unable to determine the impact of the study area on heterogeneity， and unable to determine the causality of HF and cognitive impairment.
    ConclusionThe prevalence of cognitive impairment in patients with HF in China is high and significantly affected by age， gender and other factors. Appropriate measures should be taken for prevention and timely intervention.

     

    • HTML全文
    • 参考文献(44)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回