Objective To describe the epidemiological characteristics of COVID-19 patients in Shaanxi Province from December 2021 to January 2022.

Methods All COVID-19 patients’ information was obtained from the Health Committee of Shaanxi Province. SPSS 26.0 and Stata MP 16.0 were used to analyze the distribution of Time， Population and Region. Descriptive statistical method was used to investigate the correlation between age， gender and clinical syndrome types of patients.

Results The duration of this epidemic was 43 days， and 2 080 confirmed cases in total， which distributed in cities of Xi’an （2 053 cases）， Xianyang （13 cases） ， Yan’an （13 cases） and Weinan （1 cases）. The mean age of the patients was 35.91±17.72 years old， the number of male patients was higher than that of female， and 93.7% of the patients had mild symptoms. The age and gender of the patients were statistically correlated with the symptom type （P<0.001）.

Conclusion Preventing the imported and the spread of domestic cases are currently the main measures to prevent COVID-19 in China. People should abide by the requirements and duties of epidemic prevention and control. Health management and strict quarantine should apply for keynote areas and populations. Meanwhile， the discovery of asymptomatic patients is important to prevent the potential epidemic.