Objective To understand the vaccination situation of non-national immunization program （non-NIP） vaccines in Changning District， and to provide evidence for further strengthening the management of vaccination services and guiding community health service centers to construct vaccination clinics for children and adults.

Methods Number of non-NIP vaccine doses in community health service centers， Changning District， was collected from Shanghai Immunization Information System from 2016 to 2020. Descriptive epidemiological analysis was conducted.

Results In 2020， the overall number of non-NIP vaccine doses， proportion of non-NIP vaccine doses and average number of non-NIP vaccine doses in the community health service centers， Changning District， reached up to 115 361 doses， 63.41% and 1 664.54 per 10 000 persons， respectively. Furthermore， the proportion of non-NIP vaccine doses showed a significantly upward trend （${\chi }_{\mathrm{t}\mathrm{r}\mathrm{e}\mathrm{n}\mathrm{d}}^{\mathrm{2}}$=131.110， P<0.01）. The number of non-NIP vaccine doses increased mostly in adults aged >18 years. Human papillomavirus vaccines （HPV） and influenza vaccines （InfV） had the highest increase in vaccine doses. Additionally， non-NIP vaccination peaked from September to December in adults.

Conclusion Along with the number of non-NIP vaccine doses increase， it is necessary to strengthen the management of non-NIP vaccination and explore effective measures for construction of adult vaccination clinics to meet the public demand for vaccination.